Evidence map›Paper›PMID 34539791›Full record

ArticleStem cells international2021

Chondrogenic Potential of Human Dental Pulp Stem Cells Cultured as Microtissues.

Rubén Salvador-Clavell, José Javier Martín de Llano, Lara Milián, María Oliver, Manuel Mata, Carmen Carda, María Sancho-Tello

Open access · goldAbstract read
In one paragraph

Article in Stem cells international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Current advancements in nanotechnology for stem cells.International journal of surgery (London, England) · 2024
    Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Cadaveric Adipose-Derived Stem Cells for Regenerative Medicine and Research.International journal of molecular sciences · 2023
    Article
  11. Article
  12. Chitin scaffolds derived from the marine demospongeFrontiers in bioengineering and biotechnology · 2023
    Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Rubén Salvador-ClavellDepartment of Pathology, Faculty of Medicine and Dentistry, University of Valencia, Valencia, Spain.ORCID https://orcid.org/0000-0002-8215-5932
José Javier Martín de LlanoDepartment of Pathology, Faculty of Medicine and Dentistry, University of Valencia, Valencia, Spain.ORCID https://orcid.org/0000-0001-5933-9592
Lara MiliánDepartment of Pathology, Faculty of Medicine and Dentistry, University of Valencia, Valencia, Spain.ORCID https://orcid.org/0000-0001-6889-1901
María OliverDepartment of Pathology, Faculty of Medicine and Dentistry, University of Valencia, Valencia, Spain.ORCID https://orcid.org/0000-0002-9390-1857
Manuel MataDepartment of Pathology, Faculty of Medicine and Dentistry, University of Valencia, Valencia, Spain.ORCID https://orcid.org/0000-0002-1506-7983
Carmen CardaDepartment of Pathology, Faculty of Medicine and Dentistry, University of Valencia, Valencia, Spain.ORCID https://orcid.org/0000-0002-5130-136X
María Sancho-TelloDepartment of Pathology, Faculty of Medicine and Dentistry, University of Valencia, Valencia, Spain.ORCID https://orcid.org/0000-0002-7080-2979
Universitat de València · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several tissue engineering stem cell-based procedures improve hyaline cartilage repair. In this work, the chondrogenic potential of dental pulp stem cell (DPSC) organoids or microtissues was studied. After several weeks of culture in proliferation or chondrogenic differentiation media, synthesis of aggrecan and type II and I collagen was immunodetected, and SOX9, ACAN, COL2A1, and COL1A1 gene expression was analysed by real-time RT-PCR. Whereas microtissues cultured in proliferation medium showed the synthesis of aggrecan and type II and I collagen at the 6

Identifiers

PMID34539791
PMCPMC8443354
OpenAlexW3197061941

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.