ArticleFrontiers in genetics2021
Identification of the Carbohydrate and Organic Acid Metabolism Genes Responsible for Brix in Tomato Fruit by Transcriptome and Metabolome Analysis.
Article in Frontiers in genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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22 citing papers in PubMed, 43 citations in OpenAlex.
- Genome association of carbohydrate metabolites provides new insights toward functional breeding in coffee.The plant genome · 2026Article
- Modulation of antioxidant defense and organic acid profiles in green beans (Phaseolus vulgaris L.) via salicylic acid and passive modified atmosphere packaging.BMC plant biology · 2026Article
- Nutritional Supply vs. Flavor Quality: Characterizing the Physicochemical Properties and Amino Acid Profiles of Tomatoes from Beijing and Shandong.Foods (Basel, Switzerland) · 2026Article
- Integrated widely-targeted metabolome and transcriptome analysis provide novel insights into the regulation of nutritional formation inFrontiers in plant science · 2026Article
- Morphological attributes, biochemical parameters, phytochemical constituents and antioxidant activities of endangered Citrus macroptera Mont (Hatkora.) from North-East India.Scientific reports · 2025Article
- Tomato and its relatives are breaking the genomics barriers.Journal of experimental botany · 2025Review
- Effects of exogenous Uniconazole (S3307) on oxidative damage and carbon metabolism of rice under salt stress.BMC plant biology · 2025Article
- Combined transcriptome and metabolome analysis of sugar and fatty acid of aromatic coconut and non-aromatic coconut in China.Food chemistry. Molecular sciences · 2024Article
- Impact of Cytochrome P450 Enzyme on Fruit Quality.International journal of molecular sciences · 2024Review
- Evaluation of morphological traits, biochemical parameters and seeding availability pattern among Citrus limon 'Assam lemon' accessions across Assam.Scientific reports · 2024Article
- An Integrative Transcriptomics and Proteomics Approach to Identify Putative Genes Underlying Fruit Ripening in Tomato near Isogenic Lines with Long Shelf Life.Plants (Basel, Switzerland) · 2023Article
- Identification of Chemical Constituents inMolecules (Basel, Switzerland) · 2023Article
- Comprehensive Transcriptomic and Metabolic Profiling ofInternational journal of molecular sciences · 2023Article
- Integrating Metabolomics and Proteomics Technologies Provides Insights into the Flavor Precursor Changes at Different Maturity Stages of Arabica Coffee Cherries.Foods (Basel, Switzerland) · 2023Article
- Exogenous application of ALA enhanced sugar, acid and aroma qualities in tomato fruit.Frontiers in plant science · 2023Article
- Identification of theFrontiers in plant science · 2023Article
- Transcriptome analysis of sugar and acid metabolism in young tomato fruits under high temperature and nitrogen fertilizer influence.Frontiers in plant science · 2023Article
- Applications of Delayed Luminescence for tomato fruit quality assessment across varied Sicilian cultivation zones.PloS one · 2023Article
- Article
- Modifying Anthocyanins Biosynthesis in Tomato Hairy Roots: A Test Bed for Plant Resistance to Ionizing Radiation and Antioxidant Properties in Space.Frontiers in plant science · 2022Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSugar and organic acids not only contribute to the formation of soluble solids (Brix) but also are an essential factor affecting the overall flavor intensity. However, the possible metabolic targets and molecular synthesis mechanisms remain to be further clarified.
methodsUHPLC-HRMS (ultrahigh-performance liquid chromatography and high-resolution mass spectrometry) combined with comparative transcriptome analysis were performed in fruits at green ripe (S1), turning-color (S2), and red ripe (S3) stages of two tomato genotypes TM-1 (
resultsThe fruit Brix of TM-1 was nearly twice that of TM-38 at S3. Nevertheless, TM-1 accumulated 1.84- and 2.77-fold the L-malic acid and citric acid in red ripe fruit (S3) compared with TM-38, respectively. D-glucose and D-fructose in TM-1 and TM-38 fruits tended to be similar at S3. Concomitantly, the sugar/organic acid ratio of TM-38 fruits were 23. 08-, 4. 38-, and 2.59-fold higher than that of TM-1 fruits at S1, S2, and S3, respectively. Among starch and sucrose (carbohydrate, CHO) metabolism (ko00500) genes,
conclusionCitric acid may play a more dominant role in the sugar/organic acid ratio of the tomato fruit, and the contribution of both L-malic acid and citric acid to the fruit Brix was much greater than that of D-glucose and D-fructose. Genes involved in CHO and TCA metabolism, which have a significant correlation with the sugar/organic acid ratio were considered to be the contributing factors of fruit Brix.
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