Evidence map›Paper›PMID 34539604›Full record

ArticleFrontiers in microbiology2021

Probiotics Modulate Mouse Gut Microbiota and Influence Intestinal Immune and Serotonergic Gene Expression in a Site-Specific Fashion.

Valentina Taverniti, Valentina Cesari, Giorgio Gargari, Umberto Rossi, Cristina Biddau, Cristina Lecchi, Walter Fiore, Stefania Arioli, Ivan Toschi, Simone Guglielmetti

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

  1. Pooled it
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  7. Review
  8. Article
  9. Genetic and phenotypic stability ofApplied and environmental microbiology · 2025
    Article
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  14. Microbiota influence on behavior: Integrative analysis of serotonin metabolism and behavioral profile in germ-free mice.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2024
    Article
  15. Article
  16. Review
  17. Frontiers in microbiology · 2024
    Article
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  20. Intestinal bacteria-a powerful weapon for fungal infections treatment.Frontiers in cellular and infection microbiology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Valentina TavernitiDepartment of Food, Environmental and Nutritional Sciences, Università degli Studi di Milano, Milan, Italy.
Valentina CesariDepartment of Agricultural and Environmental Sciences, Università degli Studi di Milano, Milan, Italy.
Giorgio GargariDepartment of Food, Environmental and Nutritional Sciences, Università degli Studi di Milano, Milan, Italy.
Umberto RossiDepartment of Food, Environmental and Nutritional Sciences, Università degli Studi di Milano, Milan, Italy.
Cristina BiddauDepartment of Food, Environmental and Nutritional Sciences, Università degli Studi di Milano, Milan, Italy.
Cristina LecchiDepartment of Veterinary Medicine, Università degli Studi di Milano, Milan, Italy.
Walter FioreSofar S.p.A., Trezzano Rosa, Italy.
Stefania ArioliDepartment of Food, Environmental and Nutritional Sciences, Università degli Studi di Milano, Milan, Italy.
Ivan ToschiDepartment of Agricultural and Environmental Sciences, Università degli Studi di Milano, Milan, Italy.
Simone GuglielmettiDepartment of Food, Environmental and Nutritional Sciences, Università degli Studi di Milano, Milan, Italy.
University of Milan · ITSofar (Italy) · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Probiotic microorganisms may benefit the host by influencing diverse physiological processes, whose nature and underlying mechanisms are still largely unexplored. Animal models are a unique tool to understand the complexity of the interactions between probiotic microorganisms, the intestinal microbiota, and the host. In this regard, in this pilot study, we compared the effects of 5-day administration of three different probiotic bacterial strains (

Indexed as

bifidobacteriaIL-10in vivoS24-7SERTtryptophan hydroxylasezonulin

Identifiers

PMID34539604
PMCPMC8441017
OpenAlexW3197380890

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.