Evidence map›Paper›PMID 34539597›Full record

ArticleFrontiers in microbiology2021

Ameliorative Effect of Surface Proteins of Probiotic Lactobacilli in Colitis Mouse Models.

P R Chandhni, Diwas Pradhan, Kandukuri Sowmya, Sunny Gupta, Saurabh Kadyan, Ritu Choudhary, Archita Gupta, Ganga Gulati, Rashmi Hogarehalli Mallappa, Jai K Kaushik and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Surface layer proteins fromTissue barriers · 2024
    Article
  10. Postbiotics fromFoods (Basel, Switzerland) · 2024
    Article
  11. Characteristics ofMicrobiology spectrum · 2024
    Article
  12. Article
  13. Article
  14. The Functional Roles ofJournal of microbiology and biotechnology · 2022
    Review
  15. Paraprobiotics and Postbiotics ofMicroorganisms · 2022
    Article
  16. Article
  17. Genomic Characterization ofFrontiers in bioinformatics · 2022
    Article
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

P R ChandhniMolecular Biology Unit, Dairy Microbiology Division, ICAR-National Dairy Research Institute, Karnal, India.
Diwas PradhanMolecular Biology Unit, Dairy Microbiology Division, ICAR-National Dairy Research Institute, Karnal, India.
Kandukuri SowmyaMolecular Biology Unit, Dairy Microbiology Division, ICAR-National Dairy Research Institute, Karnal, India.
Sunny GuptaMolecular Biology Unit, Dairy Microbiology Division, ICAR-National Dairy Research Institute, Karnal, India.
Saurabh KadyanMolecular Biology Unit, Dairy Microbiology Division, ICAR-National Dairy Research Institute, Karnal, India.
Ritu ChoudharyAnimal Biotechnology Center, ICAR-National Dairy Research Institute, Karnal, India.
Archita GuptaMolecular Biology Unit, Dairy Microbiology Division, ICAR-National Dairy Research Institute, Karnal, India.
Ganga GulatiMolecular Biology Unit, Dairy Microbiology Division, ICAR-National Dairy Research Institute, Karnal, India.
Rashmi Hogarehalli MallappaMolecular Biology Unit, Dairy Microbiology Division, ICAR-National Dairy Research Institute, Karnal, India.
Jai K KaushikAnimal Biotechnology Center, ICAR-National Dairy Research Institute, Karnal, India.
Sunita GroverMolecular Biology Unit, Dairy Microbiology Division, ICAR-National Dairy Research Institute, Karnal, India.
National Dairy Research Institute · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The increase in concern from viable cells of probiotics specifically in acute inflammatory conditions has led to the emergence of the concept of postbiotics as a safer alternative therapy in the field of health and wellness. The aim of the present study was to evaluate the efficacy of surface proteins from three probiotic strains in dextran sodium sulfate and trinitrobenzenesulphonic acid = induced colitis mouse models. The molecular weight of total surface proteins extracted from the three probiotic strains ranged from ∼25 to ∼250 kDa with the presence of negligible levels of endotoxins. Surface layer proteins (SLPs) (∼45 kDa) were found to be present only in the

Indexed as

anti-inflammatorycolitis micelactobacilliprobioticssurface proteins

Identifiers

PMID34539597
PMCPMC8447872
OpenAlexW3198182434

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.