Evidence map›Paper›PMID 34539399›Full record

ArticleFrontiers in pharmacology2021

Hordenine Protects Against Lipopolysaccharide-Induced Acute Lung Injury by Inhibiting Inflammation.

Xiyue Zhang, Li Du, Jinrong Zhang, Chunyan Li, Jie Zhang, Xuejiao Lv

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Combined chemoenzymatic strategy for sustainable continuous synthesis of the natural product hordenine.Green chemistry : an international journal and green chemistry resource : GC · 2022
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Xiyue ZhangDepartment of Respiratory and Critical Care Medicine, The Second Hospital of Jilin University, Changchun, China.
Li DuDepartment of Respiratory and Critical Care Medicine, The Second Hospital of Jilin University, Changchun, China.
Jinrong ZhangDepartment of Pathogeny Biology, College of Basic Medical Sciences, Jilin University, Changchun, China.
Chunyan LiDepartment of Respiratory and Critical Care Medicine, The Second Hospital of Jilin University, Changchun, China.
Jie ZhangDepartment of Respiratory and Critical Care Medicine, The Second Hospital of Jilin University, Changchun, China.
Xuejiao LvDepartment of Respiratory and Critical Care Medicine, The Second Hospital of Jilin University, Changchun, China.
Jilin University · CNSecond Affiliated Hospital of Jilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute lung injury (ALI) is a respiratory disease that leads to death in severe cases. Hordenine (Hor), a barley-derived natural product, has various biological activities, including anti-inflammatory, and anti-oxidation activities. We investigated the effect of Hor on lipopolysaccharide-induced ALI and its potential mechanism. The anti-inflammatory effects of Hor were detected using

Indexed as

acute lung injuryAutoDockhordeninelipopolysaccharidemitogen-activated protein kinaseprotein kinase B/nuclear factor-κB

Identifiers

PMID34539399
PMCPMC8440820
OpenAlexW3198834254

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.