Evidence map›Paper›PMID 34539312›Full record

ArticleFood & nutrition research2021

Screening of potential tropical fruits in protecting endothelial dysfunction

Suvara K Wattanapitayakul, Khwandow Kunchana, Wattanased Jarisarapurin, Linda Chularojmontri

Open access · goldAbstract read
In one paragraph

Article in Food & nutrition research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. UnripePreventive nutrition and food science · 2023
    Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Suvara K WattanapitayakulDepartment of Pharmacology, Faculty of Medicine, Srinakharinwirot University, Bangkok, Thailand.
Khwandow KunchanaDepartment of Pharmacology, Faculty of Medicine, Srinakharinwirot University, Bangkok, Thailand.
Wattanased JarisarapurinDepartment of Pharmacology, Faculty of Medicine, Srinakharinwirot University, Bangkok, Thailand.
Linda ChularojmontriDepartment of Preclinical Sciences, Faculty of Medicine, Thammasat University, Bangkok, Thailand.
Srinakharinwirot University · THThammasat University · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHigh consumption of antioxidant-rich fruits and vegetables reduces the endothelial damage involved in cardiovascular disease pathogenesis.

objectiveTo evaluate the phytochemical content, antioxidant and scavenging activities (FRAP, ORAC, OH

designExperimental study. The experiments were conducted

resultsThe high performance liquid chromatography (HPLC) phytochemical analysis indicated the presence of gallic acid and quercetin in all fruits, along with the overall absence of ellagic acid. Chlorogenic acid was only detected in three fruits, that is, pineapple, ripe papaya, and guava. The antioxidant and scavenging activities of all fruits were concentration-dependent. Only the H DISCUSSION: All the studied tropical fruits contained bioactive phytoantioxidants with wide ranges of antioxidant capacity and scavenging activities. The endothelial functional tests were relevant to the screening for fruits that may benefit cardiovascular health. Among the four fruits that promoted endothelial wound closure, only sugar apple and unripe papaya induced cell migration and vascular capillary-like tube formation.

conclusionSugar apple and unripe papaya are potential functional fruits that can protect against oxidative cell death and enhance endothelial wound healing.

Indexed as

cardiovascular diseasesendothelial cellsfunctional foodnitric oxidenutraceuticals

Identifiers

PMID34539312
PMCPMC8432071
OpenAlexW3196688653

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.