Evidence map›Paper›PMID 34539235›Full record

ArticleEuropean journal of inorganic chemistry2021

Biological Investigations of Ru(II) Complexes With Diverse β-diketone Ligands.

Raphael T Ryan, Dmytro Havrylyuk, Kimberly C Stevens, L Henry Moore, Sean Parkin, Jessica S Blackburn, David K Heidary, John P Selegue, Edith C Glazer

Abstract read
In one paragraph

Article in European journal of inorganic chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Ruthenium-Based Photoactivated Chemotherapy.Journal of the American Chemical Society · 2023
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Raphael T RyanDepartment of Chemistry, University of Kentucky, 505 Rose Street, Lexington, Kentucky 40506, USA.
Dmytro HavrylyukDepartment of Chemistry, University of Kentucky, 505 Rose Street, Lexington, Kentucky 40506, USA.
Kimberly C StevensDepartment of Chemistry, University of Kentucky, 505 Rose Street, Lexington, Kentucky 40506, USA.
L Henry MooreUniversity of Kentucky, Department of Molecular and Cellular Biochemistry, University of Kentucky, 741 S. Limestone, Lexington, KY 40536, USA.
Sean ParkinDepartment of Chemistry, University of Kentucky, 505 Rose Street, Lexington, Kentucky 40506, USA.
Jessica S BlackburnUniversity of Kentucky, Department of Molecular and Cellular Biochemistry, University of Kentucky, 741 S. Limestone, Lexington, KY 40536, USA.
David K HeidaryDepartment of Chemistry, University of Kentucky, 505 Rose Street, Lexington, Kentucky 40506, USA.
John P SelegueDepartment of Chemistry, University of Kentucky, 505 Rose Street, Lexington, Kentucky 40506, USA.
Edith C GlazerDepartment of Chemistry, University of Kentucky, 505 Rose Street, Lexington, Kentucky 40506, USA.

Funding

Appalachian Career Training in Oncology (ACTION) ProgramR25CA221765 · NCI · UNIVERSITY OF KENTUCKY · PI Nathan Lane Vanderford · 2018 to 2026
$3.7M
The Phosphatase PRL3 as a MYC Target and Pro-Survival Oncogene in Acute Lymphoblastic LeukemiaR37CA227656 · NCI · UNIVERSITY OF KENTUCKY · PI BLACKBURN, JESSICA S. · 2018 to 2024
$2.4M
Harnessing Single Cell Technology to Define Self-Renewal in Normal and Malignant Stem CellsDP2CA228043 · NCI · UNIVERSITY OF KENTUCKY · PI BLACKBURN, JESSICA S. · 2017 to 2017
$2.3M
Light-responsive ruthenium compounds for applications in diseaseR01GM107586 · NIGMS · UNIVERSITY OF KENTUCKY · PI GLAZER, EDITH C · 2014 to 2019
$1.7M
NCI NIH HHS DP2 CA228043NCI NIH HHS R25 CA221765NCI NIH HHS R37 CA227656NIGMS NIH HHS R01 GM107586
6 · The paper itself

Abstract

The β-diketone scaffold is a commonly used synthetic intermediate, and is a functional group found in natural products such as curcuminoids. This core structure can also act as a chelating ligand for a variety of metals. In order to assess the potential of this scaffold for medicinal inorganic chemistry, seven different κ

Identifiers

PMID34539235
PMCPMC8447810

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.