Evidence map›Paper›PMID 34539162›Full record

ArticleInfectious diseases in clinical practice (Baltimore, Md.)2021

Early Use of Remdesivir in Patients Hospitalized With COVID-19 Improves Clinical Outcomes: A Retrospective Observational Study.

Neha Paranjape, Mir Husain, Jennifer Priestley, Yashila Koonjah, Christopher Watts, Joseph Havlik

Abstract read
In one paragraph

Article in Infectious diseases in clinical practice (Baltimore, Md.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Real-world effectiveness of early remdesivir in reducing mortality among vulnerable patients hospitalized for COVID-19: Evidence for clinical pharmacists and inpatient care providers.American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists · 2026
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  11. Pharmacological treatment of COVID-19: an opinion paper.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2022
    Review
  12. Early Use of Remdesivir: A Good Start.Infectious diseases in clinical practice (Baltimore, Md.) · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Neha ParanjapeDepartment of Infectious Disease, Wellstar Kennestone Hospital.
Mir HusainDepartment of Infectious Disease, Wellstar Cobb Hospital, Marietta.
Jennifer PriestleyAnalytics and Data Science Institute, Kennesaw State University, Kennesaw.
Yashila KoonjahAnalytics and Data Science Institute, Kennesaw State University, Kennesaw.
Christopher WattsDepartment of Infectious Disease, Wellstar Douglas Hospital, Marietta, GA.
Joseph HavlikDepartment of Infectious Disease, Wellstar Cobb Hospital, Marietta.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRemdesivir treatment, like most antiviral drugs, is likely to be most effective when used early in the course of coronavirus disease 2019 (COVID-19). Optimal timing of remdesivir for the treatment of COVID-19 remains unclear.

objectivesThe aim of this study was to determine whether early treatment with remdesivir improves clinical outcomes: length of stay, need for mechanical ventilation, and death.

methodsWe conducted a retrospective observational study of patients hospitalized with COVID-19 who received remdesivir therapy within 10 days of symptom onset at a large health system in Georgia, United States.

resultsWe identified a total of 475 patients. Initiation of therapy 3 days or less from first positive SARS-CoV-2 improved length of stay (15.7 days) compared with those started on therapy more than 3 days after a positive test (19.3 days) (

conclusionsOur data show that early treatment with remdesivir in patients hospitalized with COVID-19 shortened length of stay.

Indexed as

clinical outcomesCOVID-19length of stayremdesivirSARS-CoV-2

Identifiers

PMID34539162
PMCPMC8436815

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.