Evidence map›Paper›PMID 34539134›Full record

ReviewWorld journal of gastroenterology2021

Radiomics and machine learning applications in rectal cancer: Current update and future perspectives.

Arnaldo Stanzione, Francesco Verde, Valeria Romeo, Francesca Boccadifuoco, Pier Paolo Mainenti, Simone Maurea

Abstract readReview
In one paragraph

Review in World journal of gastroenterology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Arnaldo StanzioneDepartment of Advanced Biomedical Sciences, University of Naples "Federico II", Naples 80131, Italy.
Francesco VerdeDepartment of Advanced Biomedical Sciences, University of Naples "Federico II", Naples 80131, Italy.
Valeria RomeoDepartment of Advanced Biomedical Sciences, University of Naples "Federico II", Naples 80131, Italy. valeria.romeo@unina.it.
Francesca BoccadifuocoDepartment of Advanced Biomedical Sciences, University of Naples "Federico II", Naples 80131, Italy.
Pier Paolo MainentiInstitute of Biostructures and Bioimaging, National Council of Research, Napoli 80131, Italy.
Simone MaureaDepartment of Advanced Biomedical Sciences, University of Naples "Federico II", Naples 80131, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The high incidence of rectal cancer in both sexes makes it one of the most common tumors, with significant morbidity and mortality rates. To define the best treatment option and optimize patient outcome, several rectal cancer biological variables must be evaluated. Currently, medical imaging plays a crucial role in the characterization of this disease, and it often requires a multimodal approach. Magnetic resonance imaging is the first-choice imaging modality for local staging and restaging and can be used to detect high-risk prognostic factors. Computed tomography is widely adopted for the detection of distant metastases. However, conventional imaging has recognized limitations, and many rectal cancer characteristics remain assessable only after surgery and histopathology evaluation. There is a growing interest in artificial intelligence applications in medicine, and imaging is by no means an exception. The introduction of radiomics, which allows the extraction of quantitative features that reflect tumor heterogeneity, allows the mining of data in medical images and paved the way for the identification of potential new imaging biomarkers. To manage such a huge amount of data, the use of machine learning algorithms has been proposed. Indeed, without prior explicit programming, they can be employed to build prediction models to support clinical decision making. In this review, current applications and future perspectives of artificial intelligence in medical imaging of rectal cancer are presented, with an imaging modality-based approach and a keen eye on unsolved issues. The results are promising, but the road ahead for translation in clinical practice is rather long.

Indexed as

Artificial IntelligenceRectal NeoplasmsAlgorithmsFemaleHumansMachine LearningMagnetic Resonance ImagingMaleArtificial intelligenceDeep learningMachine learningRadiogenomicsRadiomicsRectal cancer

Identifiers

PMID34539134
PMCPMC8409167

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.