Evidence map›Paper›PMID 34539009›Full record

ArticleIranian journal of medical sciences2021

The Relationship between the

Mohamed Fateen, Alia Seif, Rasha Salama, Ahmed Shams, Dalia Amin

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Iranian journal of medical sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Mohamed FateenDepartment of Clinical and Chemical Pathology, Cairo University, Cairo, Egypt.
Alia SeifDepartment of Clinical and Chemical Pathology, Cairo University, Cairo, Egypt.
Rasha SalamaDepartment of Clinical Oncology, Cairo University, Cairo, Egypt.
Ahmed ShamsDepartment of Clinical and Chemical Pathology, Cairo University, Cairo, Egypt.
Dalia AminDepartment of Clinical and Chemical Pathology, Cairo University, Cairo, Egypt.
Cairo University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Connexins (Cxs) are gap junction proteins involved in the communication between acute myeloid leukemia (AML) and stromal cells. They consist of intercellular channels termed "connexions", which can cause uncontrolled cell proliferation if dysregulated. This study aimed to evaluate the expression levels of the Methods: This cross sectional study was performed on peripheral blood samples from 60 newly diagnosed patients with AML and 40 healthy control subjects at Kasr Alainy School of Medicine, Cairo University, from June 2016 to December 2017. The quantitative real-time polymerase chain reaction (qRT-PCR) test was used to examine the relative expression level of Results: Among the patients with AML, 65% had a high Conclusion: Cx expression in samples may add to the diagnostic workup of AML. Although we found a negative correlation between

Indexed as

AdolescentAdultAgedAged, 80 and overConnexin 43ConnexinsCross-Sectional StudiesEgyptFemaleGap Junction beta-1 ProteinHumansLeukemia, Myeloid, AcuteMaleMiddle AgedRisk FactorsConnexin 43ConnexinsGap Junction beta-1 ProteinGJA1 protein, humanConnexin 43Gap junctionsGene expressionLeukemia, Myeloid, Acute

Identifiers

PMID34539009
PMCPMC8438339
OpenAlexW3168708286

What OpenQuestion holds

Textmetadata
LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.