Evidence map›Paper›PMID 34538745›Full record

ArticleJournal of cardiothoracic and vascular anesthesia2022

Six-Month Quality of Life in COVID-19 Intensive Care Unit Survivors.

Valery Likhvantsev, Giovanni Landoni, Sergey Perekhodov, Nikolay Chaus, Kristina Kadantseva, Lyubov Ermokhina, Anastasia Baeva, Mikhail Yadgarov, Levan Berikashvili, Artem Kuzovlev and 1 more

Abstract read
In one paragraph

Article in Journal of cardiothoracic and vascular anesthesia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Valery LikhvantsevV. A. Negovsky Research Institute of General Reanimatology, Moscow, Russia; First Moscow State Medical University (Sechenov University), Moscow, Russia.
Giovanni LandoniDepartment of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy. Electronic address: landoni.giovanni@hsr.it.
Sergey PerekhodovDemikhov Municipal Hospital №68, Moscow, Russia.
Nikolay ChausDemikhov Municipal Hospital №68, Moscow, Russia.
Kristina KadantsevaV. A. Negovsky Research Institute of General Reanimatology, Moscow, Russia; A. Loginov Moscow Clinical Scientific Center, Entuziastov str, 86, Moscow, Russia.
Lyubov ErmokhinaV. A. Negovsky Research Institute of General Reanimatology, Moscow, Russia; Demikhov Municipal Hospital №68, Moscow, Russia.
Anastasia BaevaV. A. Negovsky Research Institute of General Reanimatology, Moscow, Russia.
Mikhail YadgarovV. A. Negovsky Research Institute of General Reanimatology, Moscow, Russia.
Levan BerikashviliV. A. Negovsky Research Institute of General Reanimatology, Moscow, Russia.
Artem KuzovlevV. A. Negovsky Research Institute of General Reanimatology, Moscow, Russia.
Andrey GrechkoV. A. Negovsky Research Institute of General Reanimatology, Moscow, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesBecause there is increasing evidence of serious deterioration in long-term quality of life (QoL) in coronavirus 2019 (COVID-19) intensive care unit (ICU) survivors, the authors identified predictors of poor quality of life in these patients.

designProspective cohort study.

settingResearch hospital repurposed into a COVID-19 center.

participantsConsecutive patients admitted in COVID-19 ICUs between March and June 2020.

interventionsAn SF-36 questionnaire, which included physical and mental items, was used six months after patient's discharge. MEASUREMENTS AND MAIN

resultsA total of 403 patients were managed in the ICU, with a hospital mortality of 181 of 403 (44.9%), and 16 (4.0%) patients died within six months. Among the 125 questionnaire responders, only 32.0% and 52% had a normal quality of life in terms of the physical and mental component of health. Multivariate analysis identified low-molecular-weight heparin treatment in the ICU as the only modifiable factor associated with an increase in physical component of QoL odds ratio (OR) 3.341 (95% confidence interval 1.298-8.599), p = 0.012, and age ≥52 years OR 0.223 and female sex OR 0.321 were significantly associated with a decrease in the physical component. Medical history of cerebrovascular insufficiency was significantly associated with a decrease in mental component of QoL OR 0.125, and the only factor associated with an increase in the mental health component was body mass index ≥27.6 kg/m

conclusionsIn COVID-19 ICU survivors the authors identified treatment with low- molecular-weight heparin as a predictor of improved physical component of QoL at 6 months.

Indexed as

COVID-19Quality of LifeFemaleHumansIntensive Care UnitsMiddle AgedProspective StudiesSurvivorsCOVID-19critical careIntensive Carelow molecular weight heparinmortalityquality lifequality of lifeSARS-CoV-2

Identifiers

PMID34538745
PMCPMC8401277

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.