Evidence map›Paper›PMID 34538306›Full record

ReviewPediatric clinics of North America2021

COVID-19 in Children: Clinical Manifestations and Pharmacologic Interventions Including Vaccine Trials.

Ramon Galindo, Heather Chow, Chokechai Rongkavilit

Registry-linked trialAbstract readReview
In one paragraph

Review in Pediatric clinics of North America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06646744 (Safety Study About the mRNA Vaccines Against COVID-19 in Pediatric Patients), which is not on this map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06646744 completednot on this mapstarted 2022, after this paper: background citation

Safety Study About the mRNA Vaccines Against COVID-19 in Pediatric Patients (PEDIVACOV-HCSC)

TypeobservationalSponsorAna Belen Rivas PaternaRan2022 to 2023Enrolled2,100ConditionsCOVID-19 Vaccine Adverse ReactionArmsmRNA COVID-19 vaccine
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. A COVID-19 primer for primary care clinicians.Current problems in pediatric and adolescent health care · 2022
    Article
  12. Review
  13. Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ramon GalindoDepartment of Pediatrics, University of California San Francisco-Fresno Branch Campus, 155 North Fresno Street, Suite 219, Fresno, CA 93701-2302, USA.
Heather ChowDepartment of Pediatrics, University of California San Francisco-Fresno Branch Campus, 155 North Fresno Street, Suite 219, Fresno, CA 93701-2302, USA.
Chokechai RongkavilitDepartment of Pediatrics, University of California San Francisco-Fresno Branch Campus, 155 North Fresno Street, Suite 219, Fresno, CA 93701-2302, USA. Electronic address: chokechai.rongkavilit@ucsf.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Children usually present with milder symptoms of COVID-19 as compared with adults. Supportive care alone is appropriate for most children with COVID-19. Antiviral therapy may be required for those with severe or critical diseases. Currently there has been a rapid development of vaccines globally to prevent COVID-19 and several vaccines are being evaluated in children and adolescents. Currently, only the Pfizer-BioNTech messenger RNA vaccine is approved for emergency authorization use in the pediatric population ages 16 years and older.

Indexed as

AdolescentChildCOVID-19COVID-19 VaccinesHumansSafetySystemic Inflammatory Response SyndromeVaccines, SyntheticCOVID-19 VaccinesVaccines, SyntheticChildrenCoronavirusCOVID-19InfantSARS-CoV-2TreatmentVaccine

Identifiers

PMID34538306
PMCPMC8130516

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.