Evidence map›Paper›PMID 34538270›Full record

ArticleJournal of cardiothoracic surgery2021

ECMO after cardiac surgery: a single center study on survival and optimizing outcomes.

Jennifer M Brewer, Anthony Tran, Jielin Yu, M Irfan Ali, Constantine M Poulos, Jonathan Gates, Jason Gluck, David Underhill

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cardiothoracic surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jennifer M BrewerDepartment of General Surgery, University of Connecticut, 263 Farmington Ave, Farmington, CT, 06030, USA. Jenbrewer830@gmail.com.ORCID http://orcid.org/0000-0002-4729-2587
Anthony TranDepartment of General Surgery, University of Connecticut, 263 Farmington Ave, Farmington, CT, 06030, USA.
Jielin YuDepartment of General Surgery, University of Connecticut, 263 Farmington Ave, Farmington, CT, 06030, USA.
M Irfan AliDepartment of General Surgery, University of Connecticut, 263 Farmington Ave, Farmington, CT, 06030, USA.
Constantine M PoulosDepartment of General Surgery, University of Connecticut, 263 Farmington Ave, Farmington, CT, 06030, USA.
Jonathan GatesDivision of Trauma and Acute Care Surgery, Hartford Healthcare, Hartford, USA.
Jason GluckDepartment of Cardiology and Mechanical Circulatory Support, Hartford Healthcare, Hartford, USA.
David UnderhillDivision of Cardiac Surgery, Hartford Healthcare, Hartford, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe study purpose is to examine survival prognostic and extracorporeal membrane oxygenation (ECMO) application outcomes at our tertiary care center.

methodsThis is a retrospective analysis, January 2014 to September 2019. We analyzed 60 patients who underwent cardiac surgery and required peri-operative ECMO. All inpatients with demographic and intervention data was examined. 52 patients (86.6%) had refractory cardiogenic shock, 7 patients (11.6%) had pulmonary insufficiency, and 1 patient (1.6%) had hemorrhagic shock, all patients required either venous-arterial (VA) (n = 53, 88.3%), venous-venous (VV) (n = 5, 8.3%) or venous-arterial-venous (VAV) (n = 2, 3.3%) ECMO for hemodynamic support. ECMO parameters were analyzed and common postoperative complications were examined in the setting of survival with comorbidities.

resultsIn-hospital mortality was 60.7% (n = 37). Patients who survived were younger (52 ± 3.3 vs 66 ± 1.5, p < 0.001) with longer hospital stays (35 ± 4.0 vs 20 ± 1.5, p < 0.03). Survivors required fewer blood products (13 ± 2.3 vs 25 ± 2.3, p = 0.02) with a net negative fluid balance (- 3.5 ± 1.6 vs 3.4 ± 1.6, p = 0.01). Cardiac re-operations worsened survival.

conclusionECMO is a viable rescue strategy for cardiac surgery patients with a 40% survival to discharge rate. Careful attention to volume management and blood transfusion are important markers for potential survival.

Indexed as

Cardiac Surgical ProceduresExtracorporeal Membrane OxygenationHospital MortalityHumansRetrospective StudiesShock, CardiogenicTreatment OutcomeCardiac surgeryCardiac transplantationCardio-thoracic surgeryCritical careECMOLVAD

Identifiers

PMID34538270
PMCPMC8451085

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.