ArticlePhilosophical transactions of the Royal Society of London. Series B, Biological sciences2021
Predictors of zoonotic potential in helminths.
Article in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 24 citations in OpenAlex.
- Outdoor roaming of owned cats elevates risk of zoonotic pathogen exposure: A global synthesis.PLoS pathogens · 2026Article
- Field efficacy of Febantel, Pyrantel embonate and Praziquantel (Drontal® Tasty) against naturally acquired intestinal helminths of hunting dogs in southern Italy.Parasites & vectors · 2025Article
- One Health implications and first evidence of environmental contamination of helminths in soil from goat farms in Ratchaburi, Thailand.Parasitology research · 2025Article
- Pet and Stray Dogs' Contribution to Zoonotic Transmission Pathways: A Bibliometric Review.Transboundary and emerging diseases · 2025Review
- Tropical Diseases in the United States: Beyond Poverty - Advancing an Ecological Framework in Tropical Medicine.The American journal of tropical medicine and hygiene · 2024Article
- Recombinant multiepitope proteins expressed in Escherichia coli cells and their potential for immunodiagnosis.Microbial cell factories · 2024Review
- Gastrointestinal Parasites in Owned Dogs in Serbia: Prevalence and Risk Factors.Animals : an open access journal from MDPI · 2024Article
- Zoonotic Parasites and Their Association With Human Activities in Northern Tanzania: An Integrated Ecosystem Approach for One Health.Journal of parasitology research · 2024Article
- Cancerogenic parasites in veterinary medicine: a narrative literature review.Infectious agents and cancer · 2023Review
- Prevalence ofAnimals : an open access journal from MDPI · 2023Article
- A Data-driven Horizon Scan of Bacterial Pathogens at the Wildlife-livestock Interface.EcoHealth · 2022Article
- Environmental Persistence of the World's Most Burdensome Infectious and Parasitic Diseases.Frontiers in public health · 2022Review
- Predictors of zoonotic potential in helminths.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Article
- Identifying co-phylogenetic hotspots for zoonotic disease.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Article
- Functional biogeography of parasite traits: hypotheses and evidence.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Review
- Infectious disease macroecology: parasite diversity and dynamics across the globe.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Article
Corrections and comments
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Authors and funding
4 authors at 4 institutions in 3 countries.
Funding
Abstract
Helminths are parasites that cause disease at considerable cost to public health and present a risk for emergence as novel human infections. Although recent research has elucidated characteristics conferring a propensity to emergence in other parasite groups (e.g. viruses), the understanding of factors associated with zoonotic potential in helminths remains poor. We applied an investigator-directed learning algorithm to a global dataset of mammal helminth traits to identify factors contributing to spillover of helminths from wild animal hosts into humans. We characterized parasite traits that distinguish between zoonotic and non-zoonotic species with 91% accuracy. Results suggest that helminth traits relating to transmission (e.g. definitive and intermediate hosts) and geography (e.g. distribution) are more important to discriminating zoonotic from non-zoonotic species than morphological or epidemiological traits. Whether or not a helminth causes infection in companion animals (cats and dogs) is the most important predictor of propensity to cause human infection. Finally, we identified helminth species with high modelled propensity to cause zoonosis (over 70%) that have not previously been considered to be of risk. This work highlights the importance of prioritizing studies on the transmission of helminths that infect pets and points to the risks incurred by close associations with these animals. This article is part of the theme issue 'Infectious disease macroecology: parasite diversity and dynamics across the globe'.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.