ArticleThe British journal of radiology2021
CT Hounsfield unit and histogram analysis for differentiation of recent versus remote vertebral compression fractures.
Article in The British journal of radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 5 citations in OpenAlex.
- Diagnostic value of an S1-normalized CT hounsfield unit ratio for identifying acute fractures in complex thoracolumbar osteoporotic deformities.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Improved Osteoporosis Prediction in Breast Cancer Patients Using a Novel Semi-Foundational Model.Journal of imaging informatics in medicine · 2025Article
- Fat quantification of the rotator cuff muscles using CT histogram analysis in comparison with Dixon MRI sequence.The British journal of radiology · 2023Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe purpose of this study was to analyze the intraosseous tissue changes in recent vertebral compression fractures (VCFs) and to differentiate recent from remote VCFs using CT Hounsfield unit histogram analysis (HUHA).
methods65 patients with T11 to L3 VCFs were included. HUHA of 2 vertebral bodies (VBs)- a fractured VB and the closest lower-level unaffected VB-was done. The mean Hounsfield unit (HU) value and HU proportions of 5 ranges (HU ≤ 0, 0 < HU ≤ 50, 50 < HU ≤ 100, 100 < HU ≤ 150, and HU > 150) were obtained. Then, ΔHU value and ΔHU proportion were calculated by subtracting the values from the two vertebrae. Finally, the obtained values were compared between the recent and remote VCF groups and subjected to ROC curve analysis.
resultsIn recent VCF group, the ΔHU proportion (HU ≤ 0) corresponding to normal fatty marrow was lower (-0.17
conclusionCT HUHA demonstrated both trabecular bone and bone marrow changes in recent VCFs, and showed high diagnostic performance in differentiating between recent and remote VCFs. ADVANCES IN KNOWLEDGE: With its vendor neutral applicability, CT HUHA can be used for the differentiation of recent and remote VCFs.
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