Evidence map›Paper›PMID 34538075›Full record

ArticleThe Journal of neuropsychiatry and clinical neurosciences2022

Traumatic Brain Injury in Children and Adolescents: Psychiatric Disorders 24 Years Later.

Jeffrey E Max, Emily A Troyer, Hattan Arif, Florin Vaida, Elisabeth A Wilde, Erin D Bigler, John R Hesselink, Tony T Yang, Olga Tymofiyeva, Owen Wade and 1 more

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In one paragraph

Article in The Journal of neuropsychiatry and clinical neurosciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. An update on pediatric traumatic brain injury.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023
    Review
  12. Article
  13. Novel Psychiatric Disorder 6 Months After Traumatic Brain Injury in Children and Adolescents.The Journal of neuropsychiatry and clinical neurosciences · 2023
    Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Jeffrey E MaxDepartment of Psychiatry, University of California, San Diego (Max, Troyer, Arif);Rady Children's Hospital, San Diego (Max); Department of Psychiatry, University of Iowa, Iowa City (Max, Wade, Paulsen); Department of Family Medicine and Public Health, University of California, San Diego (Vaida); Department of Neurology, TBI and Concussion Center, University of Utah, Salt Lake City (Wilde, Bigler); Department of Physical Medicine and Rehabilitation, Baylor College of Medicine, Houston (Wilde); Department of Psychology, Brigham Young University, Provo, Utah (Bigler); Department of Radiology, University of California, San Diego (Hesselink); Department of Psychiatry, Division of Child and Adolescent Psychiatry, University of California, San Francisco (Yang); Department of Radiology and Biomedical Imaging, University of California, San Francisco (Tymofiyeva).
Emily A TroyerDepartment of Psychiatry, University of California, San Diego (Max, Troyer, Arif);Rady Children's Hospital, San Diego (Max); Department of Psychiatry, University of Iowa, Iowa City (Max, Wade, Paulsen); Department of Family Medicine and Public Health, University of California, San Diego (Vaida); Department of Neurology, TBI and Concussion Center, University of Utah, Salt Lake City (Wilde, Bigler); Department of Physical Medicine and Rehabilitation, Baylor College of Medicine, Houston (Wilde); Department of Psychology, Brigham Young University, Provo, Utah (Bigler); Department of Radiology, University of California, San Diego (Hesselink); Department of Psychiatry, Division of Child and Adolescent Psychiatry, University of California, San Francisco (Yang); Department of Radiology and Biomedical Imaging, University of California, San Francisco (Tymofiyeva).
Hattan ArifDepartment of Psychiatry, University of California, San Diego (Max, Troyer, Arif);Rady Children's Hospital, San Diego (Max); Department of Psychiatry, University of Iowa, Iowa City (Max, Wade, Paulsen); Department of Family Medicine and Public Health, University of California, San Diego (Vaida); Department of Neurology, TBI and Concussion Center, University of Utah, Salt Lake City (Wilde, Bigler); Department of Physical Medicine and Rehabilitation, Baylor College of Medicine, Houston (Wilde); Department of Psychology, Brigham Young University, Provo, Utah (Bigler); Department of Radiology, University of California, San Diego (Hesselink); Department of Psychiatry, Division of Child and Adolescent Psychiatry, University of California, San Francisco (Yang); Department of Radiology and Biomedical Imaging, University of California, San Francisco (Tymofiyeva).
Florin VaidaDepartment of Psychiatry, University of California, San Diego (Max, Troyer, Arif);Rady Children's Hospital, San Diego (Max); Department of Psychiatry, University of Iowa, Iowa City (Max, Wade, Paulsen); Department of Family Medicine and Public Health, University of California, San Diego (Vaida); Department of Neurology, TBI and Concussion Center, University of Utah, Salt Lake City (Wilde, Bigler); Department of Physical Medicine and Rehabilitation, Baylor College of Medicine, Houston (Wilde); Department of Psychology, Brigham Young University, Provo, Utah (Bigler); Department of Radiology, University of California, San Diego (Hesselink); Department of Psychiatry, Division of Child and Adolescent Psychiatry, University of California, San Francisco (Yang); Department of Radiology and Biomedical Imaging, University of California, San Francisco (Tymofiyeva).
Elisabeth A WildeDepartment of Psychiatry, University of California, San Diego (Max, Troyer, Arif);Rady Children's Hospital, San Diego (Max); Department of Psychiatry, University of Iowa, Iowa City (Max, Wade, Paulsen); Department of Family Medicine and Public Health, University of California, San Diego (Vaida); Department of Neurology, TBI and Concussion Center, University of Utah, Salt Lake City (Wilde, Bigler); Department of Physical Medicine and Rehabilitation, Baylor College of Medicine, Houston (Wilde); Department of Psychology, Brigham Young University, Provo, Utah (Bigler); Department of Radiology, University of California, San Diego (Hesselink); Department of Psychiatry, Division of Child and Adolescent Psychiatry, University of California, San Francisco (Yang); Department of Radiology and Biomedical Imaging, University of California, San Francisco (Tymofiyeva).
Erin D BiglerDepartment of Psychiatry, University of California, San Diego (Max, Troyer, Arif);Rady Children's Hospital, San Diego (Max); Department of Psychiatry, University of Iowa, Iowa City (Max, Wade, Paulsen); Department of Family Medicine and Public Health, University of California, San Diego (Vaida); Department of Neurology, TBI and Concussion Center, University of Utah, Salt Lake City (Wilde, Bigler); Department of Physical Medicine and Rehabilitation, Baylor College of Medicine, Houston (Wilde); Department of Psychology, Brigham Young University, Provo, Utah (Bigler); Department of Radiology, University of California, San Diego (Hesselink); Department of Psychiatry, Division of Child and Adolescent Psychiatry, University of California, San Francisco (Yang); Department of Radiology and Biomedical Imaging, University of California, San Francisco (Tymofiyeva).
John R HesselinkDepartment of Psychiatry, University of California, San Diego (Max, Troyer, Arif);Rady Children's Hospital, San Diego (Max); Department of Psychiatry, University of Iowa, Iowa City (Max, Wade, Paulsen); Department of Family Medicine and Public Health, University of California, San Diego (Vaida); Department of Neurology, TBI and Concussion Center, University of Utah, Salt Lake City (Wilde, Bigler); Department of Physical Medicine and Rehabilitation, Baylor College of Medicine, Houston (Wilde); Department of Psychology, Brigham Young University, Provo, Utah (Bigler); Department of Radiology, University of California, San Diego (Hesselink); Department of Psychiatry, Division of Child and Adolescent Psychiatry, University of California, San Francisco (Yang); Department of Radiology and Biomedical Imaging, University of California, San Francisco (Tymofiyeva).
Tony T YangDepartment of Psychiatry, University of California, San Diego (Max, Troyer, Arif);Rady Children's Hospital, San Diego (Max); Department of Psychiatry, University of Iowa, Iowa City (Max, Wade, Paulsen); Department of Family Medicine and Public Health, University of California, San Diego (Vaida); Department of Neurology, TBI and Concussion Center, University of Utah, Salt Lake City (Wilde, Bigler); Department of Physical Medicine and Rehabilitation, Baylor College of Medicine, Houston (Wilde); Department of Psychology, Brigham Young University, Provo, Utah (Bigler); Department of Radiology, University of California, San Diego (Hesselink); Department of Psychiatry, Division of Child and Adolescent Psychiatry, University of California, San Francisco (Yang); Department of Radiology and Biomedical Imaging, University of California, San Francisco (Tymofiyeva).
Olga TymofiyevaDepartment of Psychiatry, University of California, San Diego (Max, Troyer, Arif);Rady Children's Hospital, San Diego (Max); Department of Psychiatry, University of Iowa, Iowa City (Max, Wade, Paulsen); Department of Family Medicine and Public Health, University of California, San Diego (Vaida); Department of Neurology, TBI and Concussion Center, University of Utah, Salt Lake City (Wilde, Bigler); Department of Physical Medicine and Rehabilitation, Baylor College of Medicine, Houston (Wilde); Department of Psychology, Brigham Young University, Provo, Utah (Bigler); Department of Radiology, University of California, San Diego (Hesselink); Department of Psychiatry, Division of Child and Adolescent Psychiatry, University of California, San Francisco (Yang); Department of Radiology and Biomedical Imaging, University of California, San Francisco (Tymofiyeva).
Owen WadeDepartment of Psychiatry, University of California, San Diego (Max, Troyer, Arif);Rady Children's Hospital, San Diego (Max); Department of Psychiatry, University of Iowa, Iowa City (Max, Wade, Paulsen); Department of Family Medicine and Public Health, University of California, San Diego (Vaida); Department of Neurology, TBI and Concussion Center, University of Utah, Salt Lake City (Wilde, Bigler); Department of Physical Medicine and Rehabilitation, Baylor College of Medicine, Houston (Wilde); Department of Psychology, Brigham Young University, Provo, Utah (Bigler); Department of Radiology, University of California, San Diego (Hesselink); Department of Psychiatry, Division of Child and Adolescent Psychiatry, University of California, San Francisco (Yang); Department of Radiology and Biomedical Imaging, University of California, San Francisco (Tymofiyeva).
Jane S PaulsenDepartment of Psychiatry, University of California, San Diego (Max, Troyer, Arif);Rady Children's Hospital, San Diego (Max); Department of Psychiatry, University of Iowa, Iowa City (Max, Wade, Paulsen); Department of Family Medicine and Public Health, University of California, San Diego (Vaida); Department of Neurology, TBI and Concussion Center, University of Utah, Salt Lake City (Wilde, Bigler); Department of Physical Medicine and Rehabilitation, Baylor College of Medicine, Houston (Wilde); Department of Psychology, Brigham Young University, Provo, Utah (Bigler); Department of Radiology, University of California, San Diego (Hesselink); Department of Psychiatry, Division of Child and Adolescent Psychiatry, University of California, San Francisco (Yang); Department of Radiology and Biomedical Imaging, University of California, San Francisco (Tymofiyeva).
Baylor College of Medicine · USUniversity of Utah · USUniversity of California, San Diego · USUniversity of California, San Francisco · US

Funding

Clinical and Translational Science InstituteUL1TR001872 · NCATS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI COLLARD, HAROLD R, JACOBY, VANESSA · 2016 to 2025
$112.1M
Fellowship on Biological Psychiatry and NeuroscienceT32MH018399 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Pei-an (Betty) Shih · 1986 to 2026
$7.3M
Magnetoencephalography and Neurobehavioral Outcome of Pediatric Traumatic Brain InjuryR01HD088438 · NICHD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MAX, JEFFREY EDWIN · 2017 to 2021
$3.1M
Preparing for preventive clinical trials in Huntington's diseaseU01NS105509 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI PAULSEN, JANE S · 2020 to 2025
$2.5M
Integrated approach to protein biomarker identification in Huntington DiseaseU01NS082089 · NINDS · UNIVERSITY OF IOWA · PI CHELSKY, DANIEL, PAULSEN, JANE S · 2013 to 2015
$1.7M
Statistical disease modeling and clinimetrics to prepare for preventive trials in huntington diseaseU01NS103475 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI PAULSEN, JANE S · 2020 to 2022
$1.7M
Statistical disease modeling and clinimetrics to prepare for preventive trials in huntington diseaseR01NS103475 · NINDS · UNIVERSITY OF IOWA · PI PAULSEN, JANE S, ZHANG, YING · 2017 to 2018
$1.2M
SECONDARY ATTENTION DEFICIT HYPERACTIVITY DISORDERK08MH001800 · NIMH · UNIVERSITY OF CALIFORNIA SAN DIEGO · PI MAX, JEFFREY E · 2000 to 2004
$839k
Neural mechanisms of meditation training in healthy and depressed adolescents: An MRI connectome studyR61AT009864 · NCCIH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI TYMOFIYEVA, OLGA, YANG, TONY TUNG-I · 2019 to 2020
$822k
Preparing for preventive clinical trials in Huntington's diseaseR01NS105509 · NINDS · UNIVERSITY OF IOWA · PI PAULSEN, JANE S · 2018 to 2018
$658k
A Network Approach to Study Brain Plasticity in Children with Cognitive TrainingR21AT009173 · NCCIH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI TYMOFIYEVA, OLGA · 2016 to 2017
$436k
NCATS NIH HHS UL1 TR001872NCCIH NIH HHS R21 AT009173NCCIH NIH HHS R61 AT009864NICHD NIH HHS R01 HD088438NIMH NIH HHS K08 MH001800NIMH NIH HHS T32 MH018399NINDS NIH HHS R01 NS103475NINDS NIH HHS R01 NS105509NINDS NIH HHS U01 NS082089NINDS NIH HHS U01 NS103475NINDS NIH HHS U01 NS105509
6 · The paper itself

Abstract

objectiveThe investigators aimed to extend findings regarding predictive factors of psychiatric outcomes among children and adolescents with traumatic brain injury (TBI) from 2 to 24 years postinjury.

methodsYouths aged 6-14 years who were hospitalized following TBI from 1992 to 1994 were assessed at baseline for TBI severity and for preinjury psychiatric, adaptive, and behavioral functioning; family functioning; family psychiatric history; socioeconomic status; and intelligence within weeks of injury. Predictors of psychiatric outcomes following pediatric TBI at 3, 6, 12, and 24 months postinjury have previously been reported. In this study, repeat psychiatric assessments were completed at 24 years postinjury with the same cohort, now adults aged 29-39 years, with the outcome measure being presence of a psychiatric disorder not present before the TBI ("novel psychiatric disorder").

resultsFifty participants with pediatric TBI were initially enrolled, and the long-term outcome analyses focused on data from 45 individuals. Novel psychiatric disorder was present in 24 out of 45 (53%) participants. Presence of a current novel psychiatric disorder was independently predicted by the presence of a preinjury lifetime psychiatric disorder and by severity of TBI.

conclusionsLong-term psychiatric outcome (mean=23.92 years [SD=2.17]) in children and adolescents hospitalized for TBI can be predicted at the point of the initial hospitalization encounter by the presence of a preinjury psychiatric disorder and by greater injury severity.

Indexed as

Brain InjuriesBrain Injuries, TraumaticMental DisordersAdolescentAdultChildCohort StudiesHumansRisk FactorsChildhood Neuropsychiatric DisordersTraumatic Brain Injury

Identifiers

PMID34538075
OpenAlexW3199659990

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.