Evidence map›Paper›PMID 34537930›Full record

ReviewDrug delivery and translational research2022

Polymeric magnetic nanoparticles: a multitargeting approach for brain tumour therapy and imaging.

Bhavana Joshi, Abhijeet Joshi

Abstract readReview
PubMed Publisher
In one paragraph

Review in Drug delivery and translational research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Innovative applications of advanced nanomaterials in cerebrovascular imaging.Frontiers in bioengineering and biotechnology · 2024
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Bhavana JoshiDepartment of Biosciences and Biomedical Engineering, Indian Institute of Technology Indore, Room No. POD1A-710, Khandwa Road, Simrol campus, 453552, Madhya Pradesh, India.
Abhijeet JoshiDepartment of Biosciences and Biomedical Engineering, Indian Institute of Technology Indore, Room No. POD1A-710, Khandwa Road, Simrol campus, 453552, Madhya Pradesh, India. abhijeet.joshi@iiti.ac.in.ORCID 0000-0002-2177-5759

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The most challenging task in targeting the brain is trespassing the blood-brain barrier (BBB) which restricts the movement of about 98% small molecules. Targeting the central nervous system using magnetic nanoparticles may deliver the drug to the target site along with a contrast imaging property. The use of magnetic nanoparticles can become non-invasive drug targeting and a bio-imaging method for brain cancer. The strategy to apply polymeric nanoparticles as a carrier of magnetic iron oxide nanoparticles can be a promising tool as a multitherapeutic drug delivery approach involving delivery of chemotherapeutic drugs with a magnetic targeting approach, imaging, and hyperthermia. This review will highlight the existing difficulties/barriers in crossing the BBB, types of magnetic materials, polymeric carriers for functionalization of magnetic nanoparticles, and targeting strategies as therapeutic and imaging modalities. Utilization of polymeric magnetic nanoparticles as an efficient targeting platform for better drug delivery and imaging for brain cancer and future prospects are also discussed. Polymeric magnetic nanoparticles as a drug delivery and bio-imaging vehicle for brain cancer.

Indexed as

Brain NeoplasmsMagnetite NanoparticlesNanoparticlesBlood-Brain BarrierBrainDrug CarriersDrug Delivery SystemsHumansPolymersDrug CarriersMagnetite NanoparticlesPolymersBrain cancer therapyDrug deliveryHyperthermiaMagnetic nanoparticlesPolymeric nanoparticles

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.