Evidence map›Paper›PMID 34537814›Full record

ArticleCell death discovery2021

Loss of mpv17 affected early embryonic development via mitochondria dysfunction in zebrafish.

Wan-Ping Bian, Shi-Ya Pu, Shao-Lin Xie, Chao Wang, Shun Deng, Phyllis R Strauss, De-Sheng Pei

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell death discovery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Wan-Ping BianChongqing Institute of Green and Intelligent Technology, Chinese Academy of Sciences, 400714, Chongqing, China.
Shi-Ya PuChongqing Institute of Green and Intelligent Technology, Chinese Academy of Sciences, 400714, Chongqing, China.
Shao-Lin XieChongqing Institute of Green and Intelligent Technology, Chinese Academy of Sciences, 400714, Chongqing, China.
Chao WangChongqing Institute of Green and Intelligent Technology, Chinese Academy of Sciences, 400714, Chongqing, China.
Shun DengChongqing Institute of Green and Intelligent Technology, Chinese Academy of Sciences, 400714, Chongqing, China.
Phyllis R StraussDepartment of Biology, College of Science, Northeastern University, Boston, MA, 02115, USA.
De-Sheng PeiSchool of Public Health and Management, Chongqing Medical University, 400016, Chongqing, China. deshengpei@gmail.com.ORCID http://orcid.org/0000-0001-6408-9575
Chongqing Institute of Green and Intelligent Technology · CNChongqing Public Health Medical Center · CNNortheastern University · US

Funding

Chinese Academy of Sciences (CAS) noChongqing Science and Technology Commission (Chongqing Science and Technology Commission, Chongqing People's Municipal Government) No. cstc2019jcyj-msxm0700, cstc2019jcyj-zdxmX0035, CSTCCXLJRC201714, and 2019-04 Beibei
6 · The paper itself

Abstract

MVP17 encodes a mitochondrial inner-membrane protein, and mutation of human MVP17 can cause mitochondria DNA depletion syndrome (MDDS). However, the underlying function of mpv17 is still elusive. Here, we developed a new mutant with mpv17 knockout by using the CRISPR/Cas9 system. The mpv17

Identifiers

PMID34537814
PMCPMC8449779
OpenAlexW3199877219

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.