Evidence map›Paper›PMID 34537569›Full record

ArticlePlacenta2021

Quantitative T

Jeffrey N Stout, Congyu Liao, Borjan Gagoski, Esra Abaci Turk, Henry A Feldman, Carolina Bibbo, William H Barth, Scott A Shainker, Lawrence L Wald, P Ellen Grant and 1 more

Registry-linked trialOpen access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Placenta, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06290232 (Fetoscopic Laser Photocoagulation in Management of Vasa Previa - FLUMEN Study), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06290232 nawithdrawnnot on this mapstarted 2026, after this paper: background citation

Fetoscopic Laser Photocoagulation in Management of Vasa Previa - FLUMEN Study

TypeinterventionalSponsorBoston Children's HospitalRan2026 to 2028Enrolled0ConditionsVasa Previa, Pregnancy Complications, Maternal, ProcedureArmsFetoscopic Laser Photocoagulation
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Magnetic resonance imaging of the monkey fetal brain in utero.Investigative magnetic resonance imaging · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 1 country.

Jeffrey N StoutFetal and Neonatal Neuroimaging and Developmental Science Center, Boston Children's Hospital, Boston, MA, 02115, USA. Electronic address: jeffrey.stout@childrens.harvard.edu.
Congyu LiaoDepartment of Radiology, Stanford University, Stanford, CA, 94305, USA.
Borjan GagoskiFetal and Neonatal Neuroimaging and Developmental Science Center, Boston Children's Hospital, Boston, MA, 02115, USA.
Esra Abaci TurkFetal and Neonatal Neuroimaging and Developmental Science Center, Boston Children's Hospital, Boston, MA, 02115, USA.
Henry A FeldmanCenters for Clinical and Translational Research, Boston Children's Hospital, Boston, MA, 02115, USA.
Carolina BibboBrigham and Women's Hospital, Division of Maternal-Fetal Medicine, Boston, MA, 02115, USA.
William H BarthMaternal-Fetal Medicine, Obstetrics and Gynecology, Massachusetts General Hospital, Boston, MA, 02114, USA.
Scott A ShainkerMaternal-Fetal Medicine, Obstetrics and Gynecology, Beth Israel Deaconess Medical Center, Boston, MA, 02115, USA.
Lawrence L WaldAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Boston, MA, 02129, USA.
P Ellen GrantFetal and Neonatal Neuroimaging and Developmental Science Center, Boston Children's Hospital, Boston, MA, 02115, USA.
Elfar AdalsteinssonElectrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA; Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
Boston Children's Hospital · USMassachusetts General Hospital · USBeth Israel Deaconess Medical Center · USBrigham and Women's Hospital · USMassachusetts Institute of Technology · USStanford University · US

Funding

Genetic Analysis and Manipulation Core (GAEC)P50HD105351 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI SCOTT Loren POMEROY, MUSTAFA SAHIN · 2021 to 2026
$9.4M
Advanced Fetal ImagingR01EB017337 · NIBIB · BOSTON CHILDREN'S HOSPITAL · PI ADALSTEINSSON, ELFAR, GRANT, PATRICIA ELLEN · 2014 to 2018
$6.2M
Noninvasive Realtime Assessment of Placental Structure and Function with Novel MR Imaging MethodsU01HD087211 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI GRANT, PATRICIA ELLEN, WALD, LAWRENCE L · 2015 to 2015
$4.9M
Novel MRI Assessment of Placental Structure and Function Throughout PregnancyR01HD100009 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI ADALSTEINSSON, ELFAR, GRANT, PATRICIA ELLEN · 2019 to 2023
$3.6M
Magnetic Resonance Fingerprinting (MRF) for Improved High Field MRR01EB017219 · NIBIB · CASE WESTERN RESERVE UNIVERSITY · PI GRISWOLD, MARK · 2013 to 2016
$2.5M
NIBIB NIH HHS R01 EB017219NIBIB NIH HHS R01 EB017337NICHD NIH HHS P50 HD105351NICHD NIH HHS R01 HD100009NICHD NIH HHS U01 HD087211
6 · The paper itself

Abstract

introductionMR relaxometry has been used to assess placental exchange function, but methods to date are not sufficiently fast to be robust to placental motion. Magnetic resonance fingerprinting (MRF) permits rapid, voxel-wise, intrinsically co-registered T

methodsThe accuracy of FISP-based, sliding-window reconstructed MRF was tested on phantoms. MRF scans in 9-s breath holds were acquired at 3T in 31 pregnant women during air and oxygen breathing. A mixed effects model was used to test for changes in placenta relaxation times between physiological states, to assess the dependency on gestational age (GA), and the impact of placental motion.

resultsMRF estimates of known phantom relaxation times resulted in mean absolute errors for T DISCUSSION: Well-characterized, motion-robust MRF was used to acquire T

Indexed as

AdultFemaleHumansHyperoxiaImage Processing, Computer-AssistedMagnetic Resonance ImagingMiddle AgedPlacentaPregnancyYoung AdultMagnetic resonance fingerprintingPlacentaPregnancyRelaxometryT(1)T(2)

Identifiers

PMID34537569
PMCPMC8511125
OpenAlexW3194898021

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.