Evidence map›Paper›PMID 34537053›Full record

ArticleWorld journal of surgical oncology2021

Potential of combination of DCE-MRI and DWI with serum CA125 and CA199 in evaluating effectiveness of neoadjuvant chemotherapy in breast cancer.

Jun Zhang, Yongbo Huang, Jianghui Chen, Xia Wang, Hongyu Ma

Open access · goldAbstract read
In one paragraph

Article in World journal of surgical oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Jun ZhangRadiological Department, Gaomi People's Hospital, Gaomi, 261500, Shandong Province, China.
Yongbo HuangCT Radiology, Gaomi People's Hospital, Gaomi, 261500, Shandong Province, China.
Jianghui ChenDepartment of Electrical and Computer Engineering, National University of Singapore, Singapore, 117583, Singapore.
Xia WangDepartment of Electrical and Computer Engineering, National University of Singapore, Singapore, 117583, Singapore.
Hongyu MaCT Radiology, Gaomi People's Hospital, Gaomi, 261500, Shandong Province, China. qzmz25@163.com.
Gaozhou People's Hospital · CNNational University of Singapore · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo determine the potential of the combination of DCE-MRI imaging method with DWI and serum CA125 and CA199 levels in the evaluation of the efficacy of neoadjuvant chemotherapy in breast cancer patients.

methodsSixty-five breast cancer patients who received neoadjuvant chemotherapy in our hospital from April 2016 to April 2017 were selected as research subjects. The patients received 4 courses of neoadjuvant chemotherapy. Lesions were monitored using DCE-MRI and DWI, while ELISA was used to measure the serum expression levels of the tumour markers CA125 and CA199. The patients were divided into the remission group and ineffective group based on pathological diagnosis.

resultsThere were significant differences in K

conclusionCombination of DCE-MRI diagnostic imaging with DWI can directly reflect the lesions in breast cancer patients after neoadjuvant chemotherapy. Serum levels of CA125 and CA199 levels are useful for evaluation of the impact of neoadjuvant chemotherapy on breast cancer patients, including risk of cancer cell metastasis and changes in some small lesions.

Indexed as

Breast NeoplasmsNeoadjuvant TherapyContrast MediaDiffusion Magnetic Resonance ImagingFemaleHumansMagnetic Resonance ImagingPrognosisTreatment OutcomeContrast MediaBreast cancerCA125CA199DCE-MRIDWINeoadjuvant chemotherapy

Identifiers

PMID34537053
PMCPMC8449881
OpenAlexW3201218675

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.