Evidence map›Paper›PMID 34536993›Full record

Trial reportBMC anesthesiology2021

Ultrasound-guided bilateral superficial cervical plexus block enhances the quality of recovery of uremia patients with secondary hyperparathyroidism following parathyroidectomy: a randomized controlled trial.

Shenghong Hu, Teng Shu, Siqi Xu, Xia Ju, Shengbin Wang, Li Ma

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC anesthesiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Effect of Bilateral Superficial Cervical Plexus Block on Postoperative Pain in Thyroid and Parathyroid Surgery: A Systemic Review and Meta-Analysis.Medical science monitor : international medical journal of experimental and clinical research · 2025
    Pooled it
  2. Trial
  3. Trial
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Shenghong HuDepartment of Anesthesiology, Anqing Hospital Affiliated with Anhui Medical University, No.352 Renmin road, Anqing, 246003, Anhui, China.
Teng ShuDepartment of Anesthesiology, Anqing Hospital Affiliated with Anhui Medical University, No.352 Renmin road, Anqing, 246003, Anhui, China.
Siqi XuDepartment of Anesthesiology, Anqing Hospital Affiliated with Anhui Medical University, No.352 Renmin road, Anqing, 246003, Anhui, China.
Xia JuDepartment of Anesthesiology, Anqing Hospital Affiliated with Anhui Medical University, No.352 Renmin road, Anqing, 246003, Anhui, China.
Shengbin WangDepartment of Anesthesiology, Anqing Hospital Affiliated with Anhui Medical University, No.352 Renmin road, Anqing, 246003, Anhui, China. shbw1965@yeah.net.ORCID 0000-0003-1646-0864
Li MaDepartment of Thyroid and Breast Surgery, Anqing Hospital Affiliated with Anhui Medical University, No.352 Renmin road, Anqing, 246003, Anhui, China.
Anhui Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundParathyroidectomy has been proposed as a method for reducing parathyroid hormone levels. We evaluated the effects of ultrasound-guided bilateral superficial cervical plexus block (BSCPB) on the quality of recovery of uremia patients with secondary hyperparathyroidism (SHPT) following parathyroidectomy.

methodsEighty-two uremia patients who underwent parathyroidectomy and exhibited SHPT were randomly allocated to the BSCPB group or the control group (CON group). The patients received ultrasound-guided BSCPB with 7.5 ml of ropivacaine 0.5% on each side (BSCPB group) or equal amount of 0.9% normal saline (CON group). The primary outcome of the Quality of Recovery-40(QoR-40) score was recorded on the day before surgery and postoperative day 1(POD1). Secondary outcomes including total consumption of remifentanil, time to first required rescue analgesia, number of patients requiring rescue analgesia, and total consumption of tramadol during the first 24 h after surgery were recorded. The occurrence of postoperative nausea or vomiting (PONV) and the visual analogue scale (VAS) scores were assessed and recorded.

resultsThe scores on the pain and emotional state dimensions of the QoR-40 and the total QoR-40 score were higher in the BSCPB group than in the CON group on POD1 (P = 0.000). Compared with the CON group, the total consumption of remifentanil was significantly decreased in the BSCPB group (P = 0.000). The BSCPB group exhibited longer time to first required rescue analgesia (P = 0.018), fewer patients requiring rescue analgesia (P = 0.000), and lower postoperative total consumption of tramadol during the first 24 h after surgery (P = 0.000) than the CON group. The incidence of PONV was significantly lower in the BSCPB group than in the CON group (P = 0.013). The VAS scores in the BSCPB group were lower than those in the CON group at all time-points after surgery (P = 0.000).

conclusionUltrasound-guided BSCPB with ropivacaine 0.5% can enhance the quality of recovery, postoperative analgesia, and reduce the incidence of PONV in uremia patients with SHPT following parathyroidectomy.

trial registrationChiCTR1900027185 . (Prospective registered). Initial registration date was 04/11/2019.

Indexed as

Cervical Plexus BlockChinaComorbidityFemaleHumansHyperparathyroidism, SecondaryMaleMiddle AgedParathyroidectomyPostoperative Nausea and VomitingPostoperative PainProspective StudiesUltrasonography, InterventionalUremiaParathyroidectomyQuality of recoverySecondary hyperparathyroidismSuperficial cervical plexus blockUltrasound-guidedUremia

Identifiers

PMID34536993
PMCPMC8449502
OpenAlexW3200969979

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.