Evidence map›Paper›PMID 34536917›Full record

ArticleAmerican journal of otolaryngology

New onset tinnitus in the absence of hearing changes following COVID-19 infection.

Ghazal S Daher, Ashley M Nassiri, Greg Vanichkachorn, Matthew L Carlson, Brian A Neff, Colin L W Driscoll

Open access · greenAbstract readCase Reports
In one paragraph

Article in American journal of otolaryngology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 19 citations in OpenAlex.

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  6. Cochleovestibular findings linked to COVID-19: A scoping review for clinical care planning in South Africa.The South African journal of communication disorders = Die Suid-Afrikaanse tydskrif vir Kommunikasieafwykings · 2022
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Ghazal S DaherDepartment of Otolaryngology-Head and Neck Surgery, Mayo Clinic, Rochester, MN, United States of America.
Ashley M NassiriDepartment of Otolaryngology-Head and Neck Surgery, Mayo Clinic, Rochester, MN, United States of America.
Greg VanichkachornDepartment of Internal Medicine, Mayo Clinic, Rochester, MN, United States of America.
Matthew L CarlsonDepartment of Otolaryngology-Head and Neck Surgery, Mayo Clinic, Rochester, MN, United States of America.
Brian A NeffDepartment of Otolaryngology-Head and Neck Surgery, Mayo Clinic, Rochester, MN, United States of America.
Colin L W DriscollDepartment of Otolaryngology-Head and Neck Surgery, Mayo Clinic, Rochester, MN, United States of America. Electronic address: driscoll.colin@mayo.edu.
Mayo Clinic · USMayo Clinic in Florida · USWinnMed · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA variety of neurosensory symptoms including tinnitus have been associated with COVID-19 infection. While most cases of tinnitus are associated with hearing loss, here we report a case of severe tinnitus following COVID-19 infection with normal thresholds through 8000 Hz. CASE REPORT: A 49-year-old male presented with new onset severe tinnitus following COVID-19 infection. Tinnitus was bilateral, constant and nonpulsatile. Audiometric evaluation revealed normal threshold through 8000 Hz, with mild hearing loss at 16,000 Hz. Conservative measures including masking strategies failed to mitigate symptoms. A trial of gabapentin 300 mg twice per day improved tinnitus with no notable side effects.

conclusionThis patient may represent a subpopulation of patients who suffer from severe tinnitus following COVID-19 infection in the setting of largely normal hearing. The pathophysiology may be distinct from the more common hearing loss associated tinnitus and perhaps neuromodulators may play a larger role in mitigating tinnitus in this patient subset.

Indexed as

COVID-19Excitatory Amino Acid AntagonistsGabapentinHumansMaleMiddle AgedSARS-CoV-2TinnitusExcitatory Amino Acid AntagonistsGabapentinCOVID-19 infectionGabapentinHearing lossNeuromodulatorsTinnitus

Identifiers

PMID34536917
PMCPMC8429075
OpenAlexW3201582029

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.