Evidence map›Paper›PMID 34536729›Full record

ReviewCancer treatment reviews2021

Comparing cancer and cardiovascular disease trends in 20 middle- or high-income countries 2000-19: A pointer to national trajectories towards achieving Sustainable Development goal target 3.4.

Freddie Bray, Mathieu Laversanne, Bochen Cao, Cherian Varghese, Bente Mikkelsen, Elisabete Weiderpass, Isabelle Soerjomataram

Open access · greenAbstract readComparative StudyReview
In one paragraph

Review in Cancer treatment reviews, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
9.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 69 citations in OpenAlex.

  1. Review
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  7. Revista de saude publica · 2026
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  16. Variants in the neuropeptide geneAmerican journal of cancer research · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Freddie BrayCancer Surveillance Branch, International Agency for Research on Cancer, Lyon, France. Electronic address: brayf@iarc.fr.
Mathieu LaversanneCancer Surveillance Branch, International Agency for Research on Cancer, Lyon, France.
Bochen CaoDivision of Data, Analytics and Delivery for Impact, World Health Organization, Geneva, Switzerland.
Cherian VargheseDivision for UHC/Communicable Diseases and NCDs, World Health Organization, Geneva, Switzerland.
Bente MikkelsenDivision for UHC/Communicable Diseases and NCDs, World Health Organization, Geneva, Switzerland.
Elisabete WeiderpassOffice of the Director, International Agency for Research on Cancer, Lyon, France.
Isabelle SoerjomataramCancer Surveillance Branch, International Agency for Research on Cancer, Lyon, France.
Centre International de Recherche sur le Cancer · FRWorld Health Organization · CH

Funding

World Health Organization 001
6 · The paper itself

Abstract

With the 2030 Sustainable Development Goals (SDG) target of a one-third reduction in noncommunicable diseases (NCDs) less than a decade away, it is timely to assess national progress in reducing premature deaths from the two leading causes of mortality worldwide. We examine trends in the probability of dying ages 30-70 from cardiovascular disease (CVD) and cancer 2000-19 in 10 middle-income (MICs) and 10 high-income (HICs) countries with high quality data. We then predict whether the SDG target will be met in each country for CVD, cancer and for the four main NCDs combined. Downward trends were more evident in HICs relative to the MICs, and for CVD relative to cancer. CVD and cancer declines ranged from 30-60% and 20-30% in HICs over the 20-year period, but progress was less uniform among the MICs. Premature deaths from cancer exceeded CVD in nine of the 10 HICs by 2000 and in all 10 by 2019; in contrast, CVD mortality exceeded cancer in all 10 MICs in 2000 and remained the leading cause in eight countries by 2019. Two of the 10 MICs (Colombia and Kazakhstan) and seven of the HICs (Australia, Chile, Italy, New Zealand, Norway, Slovakia, and the U.K.) are predicted to meet the SDG NCDs target. Whether countries are on course to meet the target by 2030 reflects changing risk factor profiles and the extent to which effective preventative and medical care interventions have been implemented. In addition, lessons can be learned given people living with NCDs are more susceptible to severe COVID-19 illness and death.

Indexed as

Sustainable DevelopmentAdultAgedCardiovascular DiseasesDeveloped CountriesFemaleGlobal HealthHumansMaleMiddle AgedNeoplasmsSocioeconomic FactorsCancerCardiovascular diseaseEpidemiologyPremature mortalitySDGs

Identifiers

PMID34536729
PMCPMC8533484
OpenAlexW3199001555

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.