Evidence map›Paper›PMID 34536613›Full record

ArticleThe journal of allergy and clinical immunology. In practice2022

Self-Reported Physical Activity and Asthma Risk in Children.

Kim Lu, Margo Sidell, Xia Li, Emily Rozema, Dan M Cooper, Shlomit Radom-Aizik, William W Crawford, Corinna Koebnick

Abstract read
In one paragraph

Article in The journal of allergy and clinical immunology. In practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Kim LuDepartment of Pediatrics and Pediatric Exercise and Genomics Research Center, University of California, Irvine, Calif.
Margo SidellDepartment of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, Calif.
Xia LiDepartment of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, Calif.
Emily RozemaDepartment of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, Calif.
Dan M CooperDepartment of Pediatrics and Pediatric Exercise and Genomics Research Center, University of California, Irvine, Calif.
Shlomit Radom-AizikDepartment of Pediatrics and Pediatric Exercise and Genomics Research Center, University of California, Irvine, Calif.
William W CrawfordDepartment of Pediatrics and Pediatric Exercise and Genomics Research Center, University of California, Irvine, Calif; Los Angeles Medical Center, Kaiser Permanente Southern California, Los Angeles, Calif.
Corinna KoebnickDepartment of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, Calif. Electronic address: Corinna.Koebnick@kp.org.

Funding

Transforming Exercise Testing and Physical Activity Assessment in Children: New Approaches to Advance Clinical Translational Research in Child HealthU01TR002004 · NCATS · UNIVERSITY OF CALIFORNIA-IRVINE · PI COOPER, DAN M, RADOM-AIZIK, SHLOMIT · 2018 to 2022
$6.5M
Institutional Career Development CoreKL2TR001416 · NCATS · UNIVERSITY OF CALIFORNIA-IRVINE · PI CAIOZZO, VINCENT JAMES, DEMETRIOU, MICHAEL · 2015 to 2023
$5.6M
NCATS NIH HHS KL2 TR001416NCATS NIH HHS U01 TR002004
6 · The paper itself

Abstract

backgroundIncreased physical activity (PA) may protect against asthma but PA can trigger asthma symptoms.

objectiveTo investigate relationships between moderate-to-vigorous PA (MVPA) assessed during routine care visits and incident asthma.

methodsFor this retrospective cohort, 542,486 children between 2 and 17 years from 2010 to 2017 were included who had an MVPA assessment (exercise vital sign) during routine care visits. The association of MVPA and asthma was analyzed using Cox proportional hazards regression models as a function of age, with MVPA and body mass index (BMI) being time-varying factors, adjusted for race and ethnicity, socioeconomic status, and air pollution.

resultsThe mean MVPA was 5.4 (standard deviation: 4.4) hours/week. Crude asthma incidence density rate (IDR) was highest in children with <1 hour/week of MVPA (IDR: 9.07, 95% confidence interval [CI]: 8.79, 9.36) and lowest in children engaging in 4 to 7 hours/week of MVPA (IDR: 6.55, 95% CI: 6.33, 6.77). In adjusted models, an increase in MVPA was associated with lower asthma risk in children reporting 0 hour/week of MVPA (hazard ratio: 0.981, 95% CI: 0.973, 0.990). In children with ≥8 hours/week of MVPA, an increase in MVPA was associated with higher asthma risk (1.005, 95% CI: 1.002, 1.009). There was no significant BMI by MVPA interaction.

conclusionIncreasing MVPA in children with low activity levels is associated with lower asthma risk; children reporting high levels of activity may experience greater asthma risk as their activity levels increase further. Understanding the role of PA in the development of asthma and assessing MVPA during routine care visits in children may help to develop targeted interventions and guide asthma management.

Indexed as

AsthmaExerciseBody Mass IndexChildHumansRetrospective StudiesSelf ReportAsthmaChildrenObesityPhysical activity

Identifiers

PMID34536613
PMCPMC9032211

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.