ArticleInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2021
Impact of scaling up SARS-CoV-2 vaccination on COVID-19 hospitalizations in Spain.
Article in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Modeling COVID-19 dynamics in the Basque Country: characterizing population immunity profile from 2020 to 2022.BMC infectious diseases · 2025Article
- A national population-based study of mortality and risk factors in COVID-19-hospitalized patients in Spain (2020-2021).Frontiers in public health · 2025Article
- Impact and Effectiveness of COVID-19 Vaccines Based on Machine Learning Analysis of a Time Series: A Population-Based Study.Journal of clinical medicine · 2024Article
- Assessing the impact of vaccines on COVID-19 efficacy in survival rates: a survival analysis approach for clinical decision support.Frontiers in public health · 2024Article
- The molecular epidemiology of SARS-CoV-2 in the Pityusic Islands shows multiple introductions and fast replacements of variants in a touristic worldwide hot spot.Scientific reports · 2023Article
- Seven Epidemic Waves of COVID-19 in a Hospital in Madrid: Analysis of Severity and Associated Factors.Viruses · 2023Article
- Article
- Hospitalization burden and epidemiology of the COVID-19 pandemic in Spain (2020-2021).BMC infectious diseases · 2023Article
- Increased incidence of giant cell arteritis and associated stroke during the COVID-19 pandemic in Spain: A nation-wide population study.Autoimmunity reviews · 2023Review
- Observational
- Psychometric Properties of the COVID-19 Pandemic Fatigue Scale: Cross-sectional Online Survey Study.JMIR public health and surveillance · 2022Article
- Systemic Autoimmune Diseases in Patients Hospitalized with COVID-19 in Spain: A Nation-Wide Registry Study.Viruses · 2022Article
- SARS-CoV-2 Omicron variant escapes neutralizing antibodies and T cell responses more efficiently than other variants in mild COVID-19 convalescents.Cell reports. Medicine · 2022Article
- Evolution of SARS-CoV-2 in Spain during the First Two Years of the Pandemic: Circulating Variants, Amino Acid Conservation, and Genetic Variability in Structural, Non-Structural, and Accessory Proteins.International journal of molecular sciences · 2022Article
- Prior SARS-CoV-2 infection balances immune responses triggered by four EMA-approved COVID-19 vaccines: An observational study.Clinical and translational medicine · 2022Observational
- Resilience of Spike-Specific Immunity Induced by COVID-19 Vaccines against SARS-CoV-2 Variants.Biomedicines · 2022Article
- Mortality by COVID-19 Before Vaccination - One Year Experience of Hospitalized Patients in Madrid.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2022Article
- Oral antivirals for the prevention and treatment of SARS-CoV-2 infection.AIDS reviews · 2022Article
- How to Deal With Vaccine Breakthrough Infection With SARS-CoV-2 Variants.Frontiers in public health · 2022Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe advent of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines has been associated with a significant decline in coronavirus disease 2019 (COVID-19) hospitalizations and deaths. However, little is known about the benefits experienced by different population groups and/or using distinct vaccines.
methodsThe Spanish public registry was analyzed to examine associations between weekly vaccination scale-up and the incidence of COVID-19 hospitalizations by age, sex, and vaccine modality. The study period extended from January 2020 to June 2021.
resultsA total of 363 960 COVID-19 hospitalizations were recorded in Spain during the study period, with three peaks in March 2020, November 2020, and January 2021. The incidence of COVID-19 hospitalizations per 100 000 population increased exponentially with age, on average 71.5% for each decade older. Overall, individuals older than 60 years of age accounted for 65% of all COVID-19 hospitalizations. The speedy vaccination rollout since the end of 2020, with prioritization of the elderly groups, resulted in a rapid fall in COVID-19 hospitalizations starting in February 2021. The benefit was already noticed 3-4 weeks after the first dose, regardless of the vaccine modality.
conclusionsCOVID-19 hospitalizations increased exponentially with age in all three peaks of SARS-CoV-2 infection in Spain. Early mass vaccination of people over 60 years of age prevented a fourth wave of COVID-19 hospitalizations during the spring of 2021.
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