ArticleDevelopmental medicine and child neurology2022
Neurological impairment and disability in children in rural Kenya.
Article in Developmental medicine and child neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.
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Who cites it
9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 12 citations in OpenAlex.
- Prevalence, incidence, and trends of epilepsy among children and adolescents in Africa: a systematic review and meta-analysis.BMC public health · 2024Pooled it
- Barriers to access and utilization of healthcare by children with neurological impairments and disability in low-and middle-income countries: a systematic review.Wellcome open research · 2021Pooled it
- 'We discovered new ways of learning': a qualitative study of child, caregiver, and facilitator perspectives on an inclusive school readiness programme for caregivers in Bangladesh, Nepal, and Tanzania.Global health action · 2026Article
- Burden of Neurodevelopmental Disorders in Kenyan Children.JAMA network open · 2025Article
- Article
- Caregiver capabilities: Healthcare interventions for children with developmental disabilities.African journal of disability · 2025Review
- Predictors of neurodevelopment outcomes among children under 5 years old in Nairobi informal settlements.Frontiers in neuroscience · 2025Article
- Increased MCHC*RDW-SD interaction values: indicators of neurological impairment in lead-poisoned children.PeerJ · 2024Article
- The burden of neurological impairments and disability in older children measured in disability-adjusted life-years in rural Kenya.PLOS global public health · 2022Article
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7 authors at 2 institutions in 4 countries.
Funding
Abstract
aimTo investigate geographical change over time in the burden of neurological impairments in school-aged children in a demographic surveillance area.
methodWe investigated changes in neurological impairment prevalence in five domains (epilepsy and cognitive, hearing, vision, and motor impairments) using similar two-phase surveys conducted in 2001 (n=10 218) and 2015 (n=11 223) and determined changes in location-level prevalence, geographical clustering, and significant risk factors for children aged 6 to 9 years (mean 7y 6mo, SD 1y) of whom 50.4% were males. Admission trends for preterm birth, low birthweight (LBW), and encephalopathy were determined using admission data to a local hospital.
resultsOverall prevalence for any neurological impairment decreased from 61 per 1000 (95% confidence interval [CI] 48.0-74.0) in 2001 to 44.7 per 1000 (95% CI 40.9-48.6) in 2015 (p<0.001). There was little evidence of geographical variation in the prevalence of neurological impairments in either survey. The association between neurological impairments and some risk factors changed significantly with year of survey; for example, the increased association of adverse perinatal events with hearing impairments (exponentiated coefficient for the interaction=5.94, p=0.03). Annual admission rates with preterm birth (rate ratio 1.08, range 1.07-1.09), LBW (rate ratio 1.08, range 1.06-1.10), and encephalopathy (rate ratio 1.08, range 1.06-1.09) significantly increased between 2005 and 2016 (p<0.001).
interpretationThere was a significant decline in the prevalence of neurological impairments and differential changes in the associations of some risk factors with neurological impairments over the study period. Limited geographical variation suggests that similar interventions are appropriate across the defined area.
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