Evidence map›Paper›PMID 34536122›Full record

ArticleActa neuropathologica2021

GOPC:ROS1 and other ROS1 fusions represent a rare but recurrent drug target in a variety of glioma types.

Philipp Sievers, Damian Stichel, Martin Sill, Daniel Schrimpf, Dominik Sturm, Florian Selt, Jonas Ecker, Daniel Kazdal, Evelina Miele, Mariëtte E G Kranendonk and 17 more

Abstract readLetter
In one paragraph

Article in Acta neuropathologica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

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  16. Detection ofFrontiers in cell and developmental biology · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors.

Philipp Sievers *Department of Neuropathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.ORCID 0000-0003-3237-6021
Damian Stichel *Department of Neuropathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.
Martin SillHopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.
Daniel SchrimpfDepartment of Neuropathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.
Dominik SturmHopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.
Florian SeltHopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.
Jonas EckerHopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.
Daniel KazdalInstitute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.
Evelina MieleDepartment of Pediatric Onco-Hematology and Cell and Gene Therapy, IRCCS Bambino Gesù Children's Hospital, Rome, Italy.
Mariëtte E G KranendonkPrincess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
Bastiaan B J TopsPrincess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
Patricia Kohlhof-MeineckeDepartment of Pathology, Klinikum Stuttgart, Stuttgart, Germany.
Rudi BeschornerDepartment of Neuropathology, University of Tübingen, Tübingen, Germany.
Christof M KrammDivision of Pediatric Hematology and Oncology, University Medical Center Göttingen, Göttingen, Germany.
Martin HasselblattInstitute of Neuropathology, University Hospital Münster, Münster, Germany.
Guido ReifenbergerInstitute of Neuropathology, Heinrich Heine University, Düsseldorf, Germany.
David CapperCharité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Institute of Neuropathology, Berlin, Germany.
Pieter WesselingPrincess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
Albrecht StenzingerInstitute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.
Till MildeHopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.
Andrey KorshunovDepartment of Neuropathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.
Olaf WittHopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.
Stefan M PfisterHopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.
Wolfgang WickClinical Cooperation Unit Neurooncology, German Consortium for Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
Andreas von DeimlingDepartment of Neuropathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.
David T W JonesHopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.
Felix SahmDepartment of Neuropathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany. felix.sahm@med.uni-heidelberg.de.ORCID 0000-0001-5441-1962

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Adaptor Proteins, Signal TransducingBrain NeoplasmsGliomaGolgi Matrix ProteinsHumansMolecular Targeted TherapyOncogene FusionOncogene Proteins, FusionProtein-Tyrosine KinasesProto-Oncogene ProteinsAdaptor Proteins, Signal TransducingGolgi Matrix ProteinsGOPC protein, humanOncogene Proteins, FusionProtein-Tyrosine KinasesProto-Oncogene ProteinsROS1 protein, human

Identifiers

PMID34536122
PMCPMC8568855

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.