Evidence map›Paper›PMID 34536101›Full record

ReviewApplied microbiology and biotechnology2021

Yarrowia lipolytica, health benefits for animals.

Francisco A Guardiola, María Ángeles Esteban, Carlos Angulo

Abstract readReview
PubMed Publisher
In one paragraph

Review in Applied microbiology and biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 27 citations in OpenAlex.

  1. An update on clinically relevant, rare, and emergingClinical microbiology reviews · 2025
    Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Probiotic Yeasts: A Developing Reality?Journal of fungi (Basel, Switzerland) · 2024
    Review
  8. Article
  9. Article
  10. Molecules (Basel, Switzerland) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 3 countries.

Francisco A GuardiolaImmunobiology for Aquaculture Group, Department of Cell Biology and Histology, Faculty of Biology, Universidad de Murcia, Campus of International Excellence, Campus Mare Nostrum, 30100, Murcia, Spain.
María Ángeles EstebanImmunobiology for Aquaculture Group, Department of Cell Biology and Histology, Faculty of Biology, Universidad de Murcia, Campus of International Excellence, Campus Mare Nostrum, 30100, Murcia, Spain.
Carlos AnguloImmunology & Vaccinology Group, Centro de Investigaciones Biológicas del Noroeste, SC., Instituto Politécnico Nacional 195, Playa Palo de Santa Rita Sur, La Paz, B.C.S. C.P., 23096, México. eangulo@cibnor.mx.ORCID http://orcid.org/0000-0002-7965-1679
Centro de Investigaciones Biológicas Margarita Salas · ESUniversidad de Murcia · ESUniversidade do Porto · PT

Funding

fundación séneca 19883/GERM/15
6 · The paper itself

Abstract

The yeast Yarrowia lipolytica has been industrially adopted for docosahexaenoic acid and eicosapentaenoic acid production under good manufacturing practices over 2 decades. In recent years, it has claimed attention for novel biotechnological applications, such as a functional feed additive for animals. Studies have demonstrated that this yeast is safe and has probiotic and nutritional properties for mammals, birds, fish, crustaceans, and molluscs. Animals fed Y. lipolytica enhanced productive and immune parameters, as well as modulated microbiome, fatty acid composition, and biochemical profiles. Additionally, some Y. lipolytica-derived compounds have improved productive performance, immune status, and disease resistance in animals. Therefore, the aim of this review is to identify and discuss research advances on the potential use of this yeast for animals of economic interest. Challenges, opportunities, and trends were identified and envisioned in the near future for this industrially produced yeast. KEY POINTS: • Yarrowia lipolytica has probiotic and nutritional effects in animals. • Lipase2, EPA, and β-glucan from Y. lipolytica have health benefits for animals. • Y. lipolytica is envisioned in terrestrial and aquatic animal production systems.

Indexed as

YarrowiaAnimalsBiotechnologyFatty AcidsFatty AcidsAnimal productionImmunostimulantInfectionNovel probioticSurvival

Identifiers

PMID34536101
OpenAlexW3199324999

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.