Evidence map›Paper›PMID 34535856›Full record

ArticleMedical & biological engineering & computing2021

Novelty detection-based approach for Alzheimer's disease and mild cognitive impairment diagnosis from EEG.

Matous Cejnek, Oldrich Vysata, Martin Valis, Ivo Bukovsky

Open access · hybridAbstract read
In one paragraph

Article in Medical & biological engineering & computing, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 3 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 54 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Matous CejnekDepartment of Instrumentation and Control Engineering, Faculty of Mechanical Engineering, Czech Technical University in Prague, Technicka Street 4, 16607, Prague 6, Czech Republic. matousc@gmail.com.ORCID http://orcid.org/0000-0001-9130-7988
Oldrich VysataDepartment of Neurology, Faculty of Medicine in University Hospital Hradec Králové, Charles University in Prague, Sokolská 581, 500 05, Hradec Králové, Czech Republic.
Martin ValisDepartment of Neurology, Faculty of Medicine in University Hospital Hradec Králové, Charles University in Prague, Sokolská 581, 500 05, Hradec Králové, Czech Republic.
Ivo BukovskyDepartment of Computer Science, Faculty of Science, University of South Bohemia in Ceske Budejovice, Ceske Budejovice, Czech Republic.
Charles University · CZCzech Technical University in Prague · CZUniversity of South Bohemia in České Budějovice · CZ

Funding

Ministerstvo Zdravotnictví Ceské Republiky FN HK 00179906
6 · The paper itself

Abstract

Alzheimer's disease is diagnosed via means of daily activity assessment. The EEG recording evaluation is a supporting tool that can assist the practitioner to recognize the illness, especially in the early stages. This paper presents a new approach for detecting Alzheimer's disease and potentially mild cognitive impairment according to the measured EEG records. The proposed method evaluates the amount of novelty in the EEG signal as a feature for EEG record classification. The novelty is measured from the parameters of EEG signal adaptive filtration. A linear neuron with gradient descent adaptation was used as the filter in predictive settings. The extracted feature (novelty measure) is later classified to obtain Alzheimer's disease diagnosis. The proposed approach was cross-validated on a dataset containing EEG records of 59 patients suffering from Alzheimer's disease; seven patients with mild cognitive impairment (MCI) and 102 controls. The results of cross-validation yield 90.73% specificity and 89.51% sensitivity. The proposed method of feature extraction from EEG is completely new and can be used with any classifier for the diagnosis of Alzheimer's disease from EEG records.

Indexed as

Alzheimer DiseaseCognitive DysfunctionElectroencephalographyHumansAlzheimer’s diseaseEEGGradient descentLinear neural unitNovelty detection

Identifiers

PMID34535856
PMCPMC8558189
OpenAlexW3199541090

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.