Evidence map›Paper›PMID 34535840›Full record

Trial reportOral and maxillofacial surgery2022

Microcomputed tomographic analysis of bone microarchitecture after sinus augmentation with hyaluronic matrix: a case-control study.

Ezgi Gurbuz, Erhan Dursun, Alper Vatansever, Feriha Caglayan

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Oral and maxillofacial surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Recent Use of Hyaluronic Acid in Dental Medicine.Materials (Basel, Switzerland) · 2025
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ezgi GurbuzDepartment of Periodontology, Faculty of Dentistry, Kutahya Health Sciences University, 43100, Kutahya, Turkey. ezgi.dogan@ksbu.edu.tr.ORCID http://orcid.org/0000-0001-8774-8537
Erhan DursunPrivate Practice in Periodontology, Ankara, Turkey.
Alper VatanseverDepartment of Anatomy, Faculty of Medicine, Balıkesir University, Balıkesir, Turkey.
Feriha CaglayanDepartment of Periodontology, Faculty of Dentistry, Hacettepe University, Sıhhiye, 06100, Ankara, Turkey.

Funding

Hacettepe University, Scientific Research Projects Coordination Unit THD-2015-5190
6 · The paper itself

Abstract

backgroundThe aim of this study was to analyze trabecular microarchitecture of augmented sinuses with hyaluronic matrix and xenograft by microcomputed tomography, and to investigate whether hyaluronic matrix has an effect on the newly formed bone quality. MATERIALS AND

methodsThirteen patients undergoing maxillary sinus augmentation were included in this split-mouth study. Right and left sinus sites were randomly assigned to test and control group. In test group, the sinus was grafted with hyaluronic matrix and xenograft; in control group, only with xenograft. Four months after augmentation, bone samples were harvested during implant placement and analyzed for the following trabecular microarchitecture parameters using microcomputed tomography: bone volume (BV), total volume (TV), bone volume fraction (BV/TV), bone surface (BS), specific bone surface (BS/BV), bone surface density (BS/TV), trabecular thickness (Tb.Th), trabecular separation (Tb.Sp), trabecular pattern factor (Tb.Pf), and fractal dimension (FD).

resultsThere was statistically significant difference only for BS/TV parameter between two groups. BS/TV was higher in hyaluronic matrix group compared with control group.

conclusionsAddition of hyaluronic matrix to xenograft may enhance bone quality in terms of bone surface density. However, more research investigating the microstructural variation of augmented sinuses is needed with a greater sample.

Indexed as

Bone DensityMaxillary SinusCase-Control StudiesHumansMaxillaX-Ray MicrotomographyHyaluronic acidMicrocomputed tomographySinus augmentationTrabecular microarchitecture

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.