ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2022
Retained medullary cord and terminal myelocystocele as a spectrum: case report.
Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed, 5 citations in OpenAlex.
- A rare presentation of terminal myelocystocele associated with cervical dermal sinus tract: case report and literature review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026Review
- Image characteristics of retained medullary cord in secondary neurulation arrest: an observational study.Scientific reports · 2024Observational
- Retained medullary cord and caudal lipoma with histopathological presence of terminal myelocystocele in the epidural stalk.Surgical neurology international · 2023Article
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Authors and funding
6 authors at 4 institutions in 3 countries.
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No grant is acknowledged in the PubMed record.
Abstract
The caudal portion of the spinal cord, the medullary cord, is formed by secondary neurulation. One of the distinctive features of secondary neurulation compared to primary neurulation is that the medullary cord normally degenerates into a filum in humans. Various anomalies have been known to originate from degenerating process errors. One anomaly is terminal myelocystocele (TMCC), which is a closed spinal dysraphism with an elongated caudal spinal cord. The terminal part is filled with cerebrospinal fluid (CSF) and protrudes into the dorsal extradural space. Another anomaly is the retained medullary cord (RMC), which is a nonfunctioning cord-like structure extending to the cul-de-sac. In a 1-month-old boy, we identified an RMC with cystic dilatation of the caudal end extending to the epidural space at the very bottom of the cul-de-sac, resembling a degenerating terminal balloon, which is an essential feature of TMCC. Hence, this case may be considered an intermediate form between TMCC and RMC. This case provides clinical evidence that TMCC and RMC share the same pathoembryogenic origin, namely, failure of the regression phase of secondary neurulation.
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