Evidence map›Paper›PMID 34535761›Full record

Trial reportLeukemia2022

DNA-TG and risk of sinusoidal obstruction syndrome in childhood acute lymphoblastic leukemia.

Linea Natalie Toksvang, Kathrine Grell, Stine Nygaard Nielsen, Jacob Nersting, Daniel Murdy, Anthony V Moorman, Ajay Vora, Kjeld Schmiegelow

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Leukemia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Review
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Linea Natalie ToksvangDepartment of Pediatrics and Adolescent Medicine, University Hospital Rigshospitalet, Copenhagen, Denmark.ORCID http://orcid.org/0000-0002-9871-7637
Kathrine GrellSection of Biostatistics, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
Stine Nygaard NielsenDepartment of Pediatrics and Adolescent Medicine, University Hospital Rigshospitalet, Copenhagen, Denmark.
Jacob NerstingDepartment of Pediatrics and Adolescent Medicine, University Hospital Rigshospitalet, Copenhagen, Denmark.ORCID http://orcid.org/0000-0001-9144-7972
Daniel MurdyLeukaemia Research Cytogenetics Group, Translational and Clinical Research Institute, Newcastle University, Newcastle-upon-Tyne, UK.
Anthony V MoormanLeukaemia Research Cytogenetics Group, Translational and Clinical Research Institute, Newcastle University, Newcastle-upon-Tyne, UK.ORCID http://orcid.org/0000-0002-9781-6107
Ajay VoraGreat Ormond Street Hospital for Children National Health Service Trust, London, UK.
Kjeld SchmiegelowDepartment of Pediatrics and Adolescent Medicine, University Hospital Rigshospitalet, Copenhagen, Denmark. Kjeld.schmiegelow@regionh.dk.ORCID http://orcid.org/0000-0002-0829-4993
Rigshospitalet · DKNewcastle University · GBUniversity of Copenhagen · DKNational Health Service · GB

Funding

Bloodwise 10060Bloodwise 12026Bloodwise 15014
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antimetabolites, AntineoplasticAntineoplastic Combined Chemotherapy ProtocolsHepatic Veno-Occlusive DiseaseHumansPrecursor Cell Lymphoblastic Leukemia-LymphomaPrognosisThioguanineAntimetabolites, AntineoplasticThioguanine

Identifiers

PMID34535761
OpenAlexW3199535297

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.