ArticleScientific reports2021
Perioperative hemodynamic instability in pheochromocytoma and sympathetic paraganglioma patients.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17 citing papers in PubMed, 28 citations in OpenAlex.
- Silent pheochromocytoma presenting as refractory hyperglycemia without classic adrenergic symptoms.JCEM case reports · 2026Article
- Severe intraoperative hypertensive crisis during surgery for phaeochromocytoma/paraganglioma: analysis of pre-operative risk factors.Gland surgery · 2026Article
- A case of perioperative and intraoperative management of a rare vaginal paraganglioma.Gynecologic oncology reports · 2026Article
- Predicting Hemodynamic Fluctuations During Adrenalectomy for Pheochromocytoma.Diagnostics (Basel, Switzerland) · 2026Article
- Long-term persistent hypertension following surgical resection of pheochromocytoma and paraganglioma.Endocrine connections · 2026Article
- Machine Learning Model for Predicting Pheochromocytomas/Paragangliomas Surgery Difficulty: A Retrospective Cohort Study.Annals of surgical oncology · 2025Article
- Impact of neoadjuvant immunotherapy combined with chemotherapy or chemoradiotherapy on postoperative safety in locally advanced esophageal squamous cell carcinoma: a propensity score-matched retrospective cohort study.Frontiers in oncology · 2025Article
- A rare case of pheochromocytoma in a pregnant woman presenting with chest pain: extraordinary management.BMC cardiovascular disorders · 2024Article
- The combination of doxazosin and metyrosine as a preoperative treatment for pheochromocytomas and paragangliomas.Endocrine · 2024Observational
- Preoperative 3-dimensional visualization technology-assisted laparoscopic resection of ectopic pheochromocytoma surrounding the renal artery: a case description.Quantitative imaging in medicine and surgery · 2024Article
- Association between duration of phenoxybenzamine use and postoperative delirium in suspected adrenal pheochromocytoma: a retrospective cohort study.Frontiers in medicine · 2024Article
- Exploration of factors affecting hemodynamic stability following pheochromocytoma resection - cohort study.Frontiers in endocrinology · 2024Article
- The effects of perioperative dexmedetomidine infusion on hemodynamic stability during laparoscopic adrenalectomy for pheochromocytoma: a randomized study.Frontiers in medicine · 2023Article
- Abandonment of intravenous volume expansion after preoperative receipt of α-blockers in patients with adrenal pheochromocytoma was not an independent risk factor for intraoperative hemodynamic instability.Frontiers in endocrinology · 2023Article
- Pre- and peri-operative characteristics, complications and outcomes of patients with biochemically silent pheochromocytomas; a case series.Endocrine · 2022Article
- Mass size is a major predictor of hypertensive attack during surgery in patients with paraganglioma of retroperitoneum.Translational cancer research · 2022Article
- Characteristics of Intraoperative Hemodynamic Instability in Postoperatively Diagnosed Pheochromocytoma and Sympathetic Paraganglioma Patients.Frontiers in endocrinology · 2022Article
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Authors and funding
13 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
For pheochromocytoma and sympathetic paraganglioma (PPGL), surgery can be used as a curative treatment; however, the life-threatening risk of perioperative hemodynamic instability (HI) presents challenges. This study aimed to analyze the incidence and predictive factors of perioperative HI. The electronic medical records of 114 consecutive patients who underwent surgery for PPGLs at our institution were retrospectively reviewed. HI was defined as one or more episodes of systolic blood pressure > 200 mmHg or mean blood pressure < 60 mmHg during surgery. The factors predictive of perioperative HI were determined using both univariate and multivariate analyses. Intraoperative HI occurred in 79 (69.3%) patients. In multivariate analysis, α-adrenergic receptor blocker duration (days) (odds ratio, 1.015; 95% confidence interval, 1.001-1.029) was a predictor for intraoperative HI. Postoperative hypotension occurred in 36 (31.6%) patients. Higher urine epinephrine levels, and greater preoperative highest heart rate (HR) were predictive factors for postoperative hypotension in PPGL patients. Caution should be taken in perioperative management for PPGL, especially with long duration of α-adrenergic receptor blocker use, higher urine epinephrine levels, and greater preoperative highest HR.
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