Evidence map›Paper›PMID 34535474›Full record

ArticleBMJ open2021

Comparison of three different exercise training modalities (aerobic, strength and mixed) in patients with schizophrenia: study protocol for a multicentre randomised wait-list controlled trial.

Laura García-Garcés, Sergio Lacamara Cano, Yago Cebolla Meliá, María I Sánchez-López, David Marqués Azcona, Juan Francisco Lisón, Loreto Peyró-Gregori

Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04987151 (Comparison of Three Different Exercise Training Modalities), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04987151 naunknown statusnot on this map

Comparison of Three Different Exercise Training Modalities (Aerobic, Strength, and Mixed) in Patients With Schizophrenia: Study Protocol for a Multi-centre Randomised Wait-list Controlled Trial

TypeinterventionalSponsorCardenal Herrera UniversityRan2021 to 2022Enrolled105ConditionsSchizophreniaArmsExperimental-Strength training, Experimental-Aerobic training, Experimental-Strength/Aerobic training
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Laura García-GarcésDepartment of Nursing and Physiotherapy, Faculty of Health Sciences, Universidad Cardenal Herrera-CEU,CEU Universities, Moncada, Valencia, Spain lauragarciagarcesphd@gmail.com.ORCID 0000-0003-4103-3960
Sergio Lacamara CanoDepartment of Universal Health and Public Health, Valencia, Spain.
Yago Cebolla MeliáDepartment of Universal Health and Public Health, Valencia, Spain.
María I Sánchez-LópezDepartment of Nursing and Physiotherapy, Faculty of Health Sciences, Universidad Cardenal Herrera-CEU,CEU Universities, Moncada, Valencia, Spain.
David Marqués AzconaVice Presidency and Ministry of Equality and Inclusive Policies, Valencia, Spain.
Juan Francisco LisónDepartment of Biomedical Science, Faculty of Health Sciences, Universidad Cardenal Herrera-CEU,CEU Universities, Moncada, Valencia, Spain.
Loreto Peyró-GregoriDepartment of Nursing and Physiotherapy, Faculty of Health Sciences, Universidad Cardenal Herrera-CEU,CEU Universities, Moncada, Valencia, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionNumerous studies support the practice of different physical exercise modalities as an effective treatment to address the problems associated with schizophrenia, reporting that they result in improvements in patient symptoms and quality of life. Given the lack of studies comparing different types of training in controlled environments, the aim of this proposed study will be to compare the effects of three physical exercise programmes (strength, aerobic and mixed) on the symptoms, body composition, level of physical activity and health-related quality of life of patients with schizophrenia. METHODS AND ANALYSIS: A multicentre, single-blinded (evaluator), randomised, wait-list controlled (ratio 2:2:2:1) trial will be conducted with 105 patients recruited from different psychosocial care centres. The participants will be randomised into three 16-week training groups comprising 48 sessions lasting 1 hour each, or to the wait-list control group. The training groups will complete aerobic, strength or mixed (aerobic+strength) training. The participants will be assessed before, immediately after and 6 months after the end of the intervention. The patients in the wait-list control group (n=15) will receive one of the three trainings immediately after the intervention. The study variables will include positive, negative and general symptomology (Positive and Negative Syndrome Scale) as the primary outcome; as secondary outcome: body composition (by assessing body mass index, body fat mass and waist circumference), physical activity levels (International Physical Activity Questionnaire-Short Form) and quality of life (abbreviated WHO Quality of Life questionnaire). ETHICS AND DISSEMINATION: This study was approved by the ethics committees for Biomedical Research at the CEU Cardenal Herrera University of Valencia, Spain (CEI18/215). Participants will be fully informed of the purpose and procedures of the study, and written informed consent will be obtained. The results from this study will be published in peer-reviewed journals and presented in scientific conferences. TRIAL REGISTRATION NUMBER: NCT04987151.

Indexed as

Resistance TrainingSchizophreniaBody CompositionExerciseHumansMulticenter Studies as TopicQuality of LifeRandomized Controlled Trials as Topicadult psychiatryclinical trialseducation & training (see medical education & training)schizophrenia & psychotic disorders

Identifiers

PMID34535474
PMCPMC8451286

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.