Evidence map›Paper›PMID 34535211›Full record

SynthesisZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics

Safety and efficacy of eltrombopag in the treatment of children with immune thrombocytopenia: a Meta analysis.

Jin-Yun Xu, Yong Wang, Yong Wu, Jiao-Wei Gu

Open access · greenAbstract readMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 87% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jin-Yun XuDepartment of Pediatrics, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei 442000, China (Gu J-W, Email: GJW888GJW@ 163. com).
Yong WangDepartment of Pediatrics, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei 442000, China (Gu J-W, Email: GJW888GJW@ 163. com).
Yong WuDepartment of Pediatrics, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei 442000, China (Gu J-W, Email: GJW888GJW@ 163. com).
Jiao-Wei GuDepartment of Pediatrics, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei 442000, China (Gu J-W, Email: GJW888GJW@ 163. com).
Hubei University of Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo systematically assess the efficacy and safety of eltrombopag in the treatment of children with immune thrombocytopenia (ITP).

methodsPubMed, Embase, Cochrane Library, Weipu Data, CNKI, and Wanfang Data were searched for studies on eltrombopag used for the treatment of children with ITP. RevMan 5.3 and R version 3.6 were used to perform a Meta analysis of included studies.

resultsA total of 11 studies were included, with 2 randomized controlled trials and 9 cohort studies. The Meta analysis of the 9 cohort studies showed that eltrombopag had a response rate of about 70% (95%

conclusionsEltrombopag has good efficacy and safety as a second-line treatment regimen for children with ITP.

Indexed as

Purpura, Thrombocytopenic, IdiopathicBenzoatesChildHumansHydrazinesPyrazolesReceptors, FcThrombopoietinBenzoateseltrombopagHydrazinesPyrazolesReceptors, FcThrombopoietinChildEfficacyEltrombopagImmune thrombocytopeniaMeta analysisSafety

Identifiers

PMID34535211
PMCPMC8480157
OpenAlexW3201206992

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.