ArticleBMC microbiology2021
Genetic characterization of Carbapenem-Resistant Escherichia coli from China, 2015-2017.
Article in BMC microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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27 citing papers in PubMed, 36 citations in OpenAlex.
- Whole genome analysis of a multidrug-resistant blaBMC microbiology · 2026Article
- Cross-regional dynamics of antibiotic resistance (AR): Genomic evidence of transmission forEco-Environment & Health · 2026Article
- Cross-species transmission ofFrontiers in cellular and infection microbiology · 2026Review
- The WHO priority list of antibiotic-resistant bacteria: challenges and opportunities for next-generation antimicrobial development.Frontiers in pharmacology · 2026Review
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- The emergence of highly resistant and hypervirulentEmerging microbes & infections · 2025Article
- Frog Skin Peptides Hylin-a1, AR-23, and RV-23: Promising Tools Against Carbapenem-ResistantAntibiotics (Basel, Switzerland) · 2025Article
- Transcriptional response study of auto inducer-2 regulatory system in Escherichia coli harboring blaBMC microbiology · 2025Article
- Prevalence and genomic insights of carbapenem resistant and ESBL producing Multidrug resistant Escherichia coli in urinary tract infections.Scientific reports · 2025Article
- Emergence and transmission of Carbapenem-resistantFrontiers in veterinary science · 2025Article
- Microbiological findings of dental implants among irradiated head and neck cancer patients.Bioinformation · 2025Article
- Molecular epidemiology of carbapenem-resistantPeerJ · 2025Article
- Characterization of novel sequence type 12531 and O8:H7 serotype carbapenem-resistantAntimicrobial agents and chemotherapy · 2024Article
- Emergence of Carbapenem-Resistant UropathogenicPathogens (Basel, Switzerland) · 2024Article
- Prevalence and molecular characteristics of carbapenem-resistantJournal of veterinary science · 2024Article
- Review
- Global emergence of a hypervirulent carbapenem-resistant Escherichia coli ST410 clone.Nature communications · 2024Article
- Genetic landscape of ESBL producing international clone ST410 ofFrontiers in cellular and infection microbiology · 2024Article
- Antimicrobial resistance and molecular epidemiology of carbapenem-resistant Escherichia coli from urinary tract infections in Shandong, China.International microbiology : the official journal of the Spanish Society for Microbiology · 2023Review
- Epidemiological Characteristics of Carbapenem-ResistantPathogens (Basel, Switzerland) · 2023Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe molecular characteristics of carbapenem-resistant Escherichia coli (CREco) remain unclear.
methodsWe conducted a multi-center bacterial resistance monitoring project from 2015 to 2017.The minimum inhibitory concentrations ofCREco were determined bybroth microdilution method. The genome sequencing of CREcoisolates was performed, and single-nucleotide polymorphism (SNP) was analyzed.
resultsA total of 144CREcoisolatescollected from 10 cities in China were involved in this study. ST167 (n = 43) is the most popular type, followed by ST410(n = 14), ST131(n = 9). There were 102 (70.83%) CREco isolates that produced various NDMs, including NDM-1 (n = 16), NDM-4(n = 1), NDM-5(n = 79), NDM-6(n = 2) and NDM-9(n = 4). In addition, 15 isolates produced KPC-2, three isolates wereIMP-4 positive, and three isolates produced OXA-48. Genetic relatedness and phylogenetic analysis showed that isolates with the same ST had a high degree of homology. Some STs (including ST167, ST410, ST131, ST46, ST405 and ST617) exhibited a trend of outbreak.
conclusionsThe majority of CREco belonged to ST167, followed by ST410 and ST131, and most of them carried various NDM-coding genes. The spread of high-risk clones of CREco has occurred in different regions of China.
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