Evidence map›Paper›PMID 34534664›Full record

Trial reportJournal of cardiac failure2022

The HEART Camp Exercise Intervention Improves Exercise Adherence, Physical Function, and Patient-Reported Outcomes in Adults With Preserved Ejection Fraction Heart Failure.

Windy W Alonso, Kevin A Kupzyk, Joseph F Norman, Scott W Lundgren, Alfred Fisher, Merry L Lindsey, Steven J Keteyian, Bunny J Pozehl

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of cardiac failure, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01658670 (HEART Camp), which is not on this map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01658670 nacompletednot on this map

HEART Camp: Promoting Adherence to Exercise in Patients With Heart Failure

TypeinterventionalSponsorUniversity of NebraskaRan2012 to 2018Enrolled245ConditionsHeart FailureArmsEnhanced Usual Care Group, HEART Camp (HC) Intervention Group
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Exercise-based cardiac rehabilitation for adults with heart failure.The Cochrane database of systematic reviews · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Windy W AlonsoCollege of Nursing, University of Nebraska Medical Center, Omaha, Nebraska. Electronic address: windy.alonso@unmc.edu.
Kevin A KupzykCollege of Nursing, University of Nebraska Medical Center, Omaha, Nebraska.
Joseph F NormanCollege of Allied Health Professions, University of Nebraska Medical Center, Omaha, Nebraska.
Scott W LundgrenDivision of Cardiology, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, Nebraska.
Alfred FisherDivision of Geriatrics, Gerontology, and Palliative Medicine, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, Nebraska.
Merry L LindseyDepartment of Cellular and Integrative Physiology, Center for Heart and Vascular Research, University of Nebraska Medical Center, Omaha, Nebraska; Research Service, Nebraska-Western Iowa Health Care System, Omaha, Nebraska.
Steven J KeteyianHenry Ford Health System, Detroit, Michigan.
Bunny J PozehlCollege of Nursing, University of Nebraska Medical Center, Omaha, Nebraska.
University of Nebraska Medical Center · USNebraska Medical Center · USHenry Ford Health System · US

Funding

Tracking and Evaluation CoreU54GM115458 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI GUDA, CHITTIBABU · 2016 to 2025
$42.8M
Heart Camp: Promoting Adherence to Exercise in Patients with Heart FailureR01HL112979 · NHLBI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI POZEHL, BUNNY · 2012 to 2016
$3.3M
NHLBI NIH HHS R01 HL112979NIGMS NIH HHS U54 GM115458
6 · The paper itself

Abstract

backgroundDespite exercise being one of few strategies to improve outcomes for individuals with heart failure with preserved ejection fraction (HFpEF), exercise clinical trials in HFpEF are plagued by poor interventional adherence. Over the last 2 decades, our research team has developed, tested, and refined Heart failure Exercise And Resistance Training (HEART) Camp, a multicomponent behavioral intervention to promote adherence to exercise in HF. We evaluated the effects of this intervention designed to promote adherence to exercise in HF focusing on subgroups of participants with HFpEF and heart failure with reduced ejection fraction (HFrEF). METHODS AND

resultsThis randomized controlled trial included 204 adults with stable, chronic HF. Of those enrolled, 59 had HFpEF and 145 had HFrEF. We tested adherence to exercise (defined as ≥120 minutes of moderate-intensity [40%-80% of heart rate reserve] exercise per week validated with a heart rate monitor) at 6, 12, and 18 months. We also tested intervention effects on symptoms (Patient-Reported Outcomes Measurement Information System-29 and dyspnea-fatigue index), HF-related health status (Kansas City Cardiomyopathy Questionnaire), and physical function (6-minute walk test). Participants with HFpEF (n = 59) were a mean of 64.6 ± 9.3 years old, 54% male, and 46% non-White with a mean ejection fraction of 55 ± 6%. Participants with HFpEF in the HEART Camp intervention group had significantly greater adherence compared with enhanced usual care at both 12 (43% vs 14%, phi = 0.32, medium effect) and 18 months (56% vs 0%, phi = 0.67, large effect). HEART Camp significantly improved walking distance on the 6-minute walk test (η

conclusionsA multicomponent, behavioral intervention is associated with improvements in long-term adherence to exercise, physical function, and patient-reported outcomes in adults with HFpEF and anxiety in HFrEF. Our results provide a strong rationale for a large HFpEF clinical trial to validate these findings and examine interventional mechanisms and delivery modes that may further promote adherence and improve clinical outcomes in this population. CLINICAL

trial registrationURL: https://clinicaltrials.gov/. Unique identifier: NCT01658670.

Indexed as

CardiomyopathiesHeart FailureHeart Failure, DiastolicAdultAgedExerciseExercise TherapyFemaleHumansMaleMiddle AgedPatient Reported Outcome MeasuresQuality of LifeStroke VolumeadherenceexerciseHeart failureheart failure with preserved ejection fractionheart failure with reduced ejection fraction

Identifiers

PMID34534664
PMCPMC8920955
OpenAlexW3200133047

What OpenQuestion holds

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LicenceTDM
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.