ArticleNeuron2021
A precise and adaptive neural mechanism for predictive temporal processing in the frontal cortex.
Article in Neuron, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
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Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.
- Comprehensive investigation of predictive processing: A cross- and within-cognitive domains fMRI meta-analytic approach.Human brain mapping · 2024Pooled it
- Predictive processing in time perception: Assessing prediction error minimization in the sub-second range.Cognitive, affective & behavioral neuroscience · 2026Article
- Leveraging insights from neuroscience to build adaptive artificial intelligence.Nature neuroscience · 2026Review
- Article
- How the brain predicts timing: distinct network hubs for predicting and evaluating auditory sensory events.Frontiers in neuroscience · 2026Article
- Belief embodiment through eye movements facilitates memory-guided navigation.Nature communications · 2025Article
- Dynamic Brain Activation and Connectivity in Elite Golfers During Distinct Golf Swing Phases: An fMRI Study.Brain sciences · 2025Article
- Common electrophysiological signatures of relative magnitude in both space and time.Scientific reports · 2025Article
- Context rescales a social action code in a hormone-sensitive network.bioRxiv : the preprint server for biology · 2025Article
- Control Principles of Neural Dynamics Revealed by the Neurobiology of Timing.Annual review of neuroscience · 2025Review
- Article
- Uncertainty estimation with prediction-error circuits.Nature communications · 2025Article
- Striatal arbitration between choice strategies guides few-shot adaptation.Nature communications · 2025Article
- Hierarchical representations of relative numerical magnitudes in the human frontoparietal cortex.Nature communications · 2025Article
- Dynamic tracking of objects in the macaque dorsomedial frontal cortex.Nature communications · 2025Article
- Stable sequential dynamics in prefrontal cortex represents subjective estimation of time.eLife · 2024Article
- Prediction-error signals in anterior cingulate cortex drive task-switching.Nature communications · 2024Article
- Computational role of structure in neural activity and connectivity.Trends in cognitive sciences · 2024Review
- Duration of Untreated Prodromal Psychosis and Cognitive Impairments.JAMA network open · 2024Article
- Temporal Information Processing in the Cerebellum and Basal Ganglia.Advances in experimental medicine and biology · 2024Review
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
Abstract
The theory of predictive processing posits that the brain computes expectations to process information predictively. Empirical evidence in support of this theory, however, is scarce and largely limited to sensory areas. Here, we report a precise and adaptive mechanism in the frontal cortex of non-human primates consistent with predictive processing of temporal events. We found that the speed of neural dynamics is precisely adjusted according to the average time of an expected stimulus. This speed adjustment, in turn, enables neurons to encode stimuli in terms of deviations from expectation. This lawful relationship was evident across multiple experiments and held true during learning: when temporal statistics underwent covert changes, neural responses underwent predictable changes that reflected the new mean. Together, these results highlight a precise mathematical relationship between temporal statistics in the environment and neural activity in the frontal cortex that may serve as a mechanism for predictive temporal processing.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.