ArticleScience advances2021
Ancient genomics reveals tripartite origins of Japanese populations.
Article in Science advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed.
- A highly prevalent lupus risk haplotype increases IRF7-dependent induction of IFN-α, enhancing antiviral defense and exacerbating autoimmunity.American journal of human genetics · 2026Article
- Genomic characterization of historical Jinlingnan individuals: insights into genetic continuity and trans-Eurasian signals in eastern China.Human genetics · 2026Article
- Jomon genomics reveal cold adaptation in Upper Paleolithic hunter-gatherers of eastern Eurasia.Science advances · 2026Article
- High-coverage ancient genomes reveal divergent population histories and prehistoric starch-related genetic variation in Japan.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Ancient genomes reveal an extensive kinship network and endogamy in a Three-Kingdoms period society in Korea.Science advances · 2026Article
- Global patterns of natural selection inferred using ancient DNA.bioRxiv : the preprint server for biology · 2026Article
- Ancient genomes reveal early-stage admixture and genetic diversity in the Northwestern Kyushu Yayoi.Scientific reports · 2026Article
- The genetic history around the southeastern Mongolian Plateau traces Neolithic cultural diffusions in northern East Asia.Innovation (Cambridge (Mass.)) · 2026Article
- Demographic history of the Jomon people: insights from whole-mitogenome analysis.Anthropological science : journal of the Anthropological Society of Nippon = Jinruigaku zasshi · 2026Article
- The effects of environmental stress on third molar agenesis in humans and its population differences.Anthropological science : journal of the Anthropological Society of Nippon = Jinruigaku zasshi · 2026Article
- Ancient genomes give insight into 160,000 years of East Asian population dynamics and biological adaptation.Genome biology · 2025Review
- Lipid residue analysis reveals divergent culinary practices in Japan and Korea at the dawn of intensive agriculture.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Ancient genomes in Southwest China revealed genetic interactions among diverse populations in the historical period.BMC biology · 2025Article
- Profiling of runs of homozygosity from whole-genome sequence data in Japanese biobank.Journal of human genetics · 2025Article
- Fine-scale population structure of JapaneseMicrobial genomics · 2025Article
- Urbanization and genetic homogenization in the medieval Low Countries revealed through a ten-century paleogenomic study of the city of Sint-Truiden.Genome biology · 2025Article
- Establishment and validation of a DIP panel for forensic ancestry inference and personal identification.Human genomics · 2025Article
- Human dispersal into East Eurasia: ancient genome insights and the need for research on physiological adaptations.Journal of physiological anthropology · 2025Review
- East Asian Gene flow bridged by northern coastal populations over past 6000 years.Nature communications · 2025Article
- Genetic analysis of a Yayoi individual from the Doigahama site provides insights into the origins of immigrants to the Japanese Archipelago.Journal of human genetics · 2025Article
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Authors and funding
16 authors.
Funding
Abstract
Prehistoric Japan underwent rapid transformations in the past 3000 years, first from foraging to wet rice farming and then to state formation. A long-standing hypothesis posits that mainland Japanese populations derive dual ancestry from indigenous Jomon hunter-gatherer-fishers and succeeding Yayoi farmers. However, the genomic impact of agricultural migration and subsequent sociocultural changes remains unclear. We report 12 ancient Japanese genomes from pre- and postfarming periods. Our analysis finds that the Jomon maintained a small effective population size of ~1000 over several millennia, with a deep divergence from continental populations dated to 20,000 to 15,000 years ago, a period that saw the insularization of Japan through rising sea levels. Rice cultivation was introduced by people with Northeast Asian ancestry. Unexpectedly, we identify a later influx of East Asian ancestry during the imperial Kofun period. These three ancestral components continue to characterize present-day populations, supporting a tripartite model of Japanese genomic origins.
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