Evidence map›Paper›PMID 34533748›Full record

ArticleEnvironmental science and pollution research international2022

Spirulina platensis protects against microcystin-LR-induced toxicity in rats.

Mousa O Germoush, Maged M A Fouda, Mohamed Kamel, Mohamed M Abdel-Daim

Abstract read
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In one paragraph

Article in Environmental science and pollution research international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. [Long-term low-dose microcystin-LR exposure induces renal injury in mice by activating PI3K/AKT signaling pathway].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Mousa O GermoushBiology Department, College of Science, Jouf University, Sakaka, Saudi Arabia.
Maged M A FoudaBiology Department, College of Science, Jouf University, Sakaka, Saudi Arabia.
Mohamed KamelDepartment of Medicine and Infectious Diseases, Faculty of Veterinary Medicine, Cairo University, Giza, 12211, Egypt.
Mohamed M Abdel-DaimDepartment of Pharmaceutical Sciences, Pharmacy Program, Batterjee Medical College, P.O. Box 6231, Jeddah, 21442, Saudi Arabia. abdeldaim.m@vet.suez.edu.eg.ORCID http://orcid.org/0000-0002-4341-2713
Al-Azhar University · EGCairo University · EGJouf University · SASuez Canal University · EG

Funding

Al Jouf University 40/370
6 · The paper itself

Abstract

Microcystis aeruginosa produces an abundant cyanotoxin (microcystins (MCs) in freshwater supplies. MCs have adverse health hazards to animals and humans. Microcystin-leucine-arginine (microcystin-LR or MC-LR) is the most studied among these MCs due to their high toxicity. So, this study was designed to evaluate the possible therapeutic role of the natural algal food supplement, Spirulina platensis (SP), against MC-LR-induced toxic effects in male Wistar rats. Forty rats were randomly divided into five groups. Control and SP groups orally administered distilled water and SP (1000 mg/kg/daily), respectively, for 21 days. MC-LR group was intraperitoneally injected with MC-LR (10 μg/kg/day) for 14 days. MC-LR-SP

Indexed as

Marine ToxinsMicrocystinsAnimalsAntioxidantsGlutathioneLiverMaleOxidative StressRatsRats, WistarSpirulinaAntioxidantscyanoginosin LRGlutathioneMarine ToxinsMicrocystinsAntioxidantBrainHeartKidneyLiverMC-LRMicroalgaeOxidative stressReactive oxygen species

Identifiers

PMID34533748
OpenAlexW3201425393

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.