Evidence map›Paper›PMID 34533652›Full record

ReviewSchmerz (Berlin, Germany)2022

[Kratom - a short review for pain medicine].

Florian Lautenschlager, Manfred Weiss, Sigrun Feuerer, Norbert Wodarz

Abstract readReview
In one paragraph

Review in Schmerz (Berlin, Germany), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Florian LautenschlagerZentrum für Suchtmedizin, Klinik und Poliklinik für Psychiatrie und Psychotherapie der Universität Regensburg am Bezirksklinikum Regensburg, Universitätsstraße 84, 93053, Regensburg, Deutschland. florian.lautenschlager@medbo.de.ORCID http://orcid.org/0000-0003-2984-8526
Manfred WeissKlinik für Anästhesiologie und Intensivmedizin, Universitätsklinikum Ulm, Albert-​Einstein-Allee 23, 89081, Ulm, Deutschland.ORCID http://orcid.org/0000-0003-4851-6439
Sigrun FeuererSchmerztherapie, Goldbergklinik Kelheim, Traubenweg 3, 93309, Kelheim, Deutschland.ORCID http://orcid.org/0000-0002-8026-8132
Norbert WodarzZentrum für Suchtmedizin, Klinik und Poliklinik für Psychiatrie und Psychotherapie der Universität Regensburg am Bezirksklinikum Regensburg, Universitätsstraße 84, 93053, Regensburg, Deutschland.ORCID http://orcid.org/0000-0001-9070-8448

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundConsumption of the psychotropic plant kratom (botanical name: Mitragyna speciosa) is sometimes used for the self-medication of chronic or acute pain. An increase in the use is possible in Germany in the future.

objectiveThis review provides an overview on kratom for pain specialists. The topics of the review are the pharmacological aspects, the mental effects, the effects on pain and the risks of kratom including possible addiction. MATERIAL AND

methodsWe conducted a review of literature in PubMed published until 15 January 2021 resulting in 426 publications of which 8 were specifically concerned with the topic of kratom and pain.

resultsIn addition to other alkaloids, kratom also contains 7‑hydroxymitragynine, which is active on opioid receptors. The use of kratom is not without risks, e.g. because there is no standardized form of administration as well as the possibility of direct damage to health and of addiction. DISCUSSION: There are currently no evidence-based reasons to recommend the use of kratom as an analgesic. It is important for pain specialists to ask patients about a possible abuse of kratom and to be able to inform the patients about the potential risks of kratom.

Indexed as

MitragynaAnalgesicsGermanyHumansPainAnalgesicsAddiction medicinePainPain specialistsPharmacologyRisks

Identifiers

PMID34533652
PMCPMC8447806

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.