Evidence map›Paper›PMID 34533589›Full record

ArticleArchives of dermatological research2022

Atopic dermatitis is not associated with SARS-CoV-2 outcomes.

Uros Rakita, Trisha Kaundinya, Armaan Guraya, Kamaria Nelson, Brittany Maner, Jaya Manjunath, Gabrielle Schwartzman, Brittany Lane, Jonathan I Silverberg

Open access · bronzeAbstract read
In one paragraph

Article in Archives of dermatological research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
  4. Article
  5. Inflammation Causes Exacerbation of COVID-19: How about Skin Inflammation?International journal of molecular sciences · 2022
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 2 countries.

Uros RakitaChicago Medical School, Rosalind Franklin University, North Chicago, IL, 60064, USA.ORCID https://orcid.org/0000-0002-8447-4283
Trisha KaundinyaNorthwestern Feinberg School of Medicine, Chicago, IL, 60611, USA.ORCID https://orcid.org/0000-0002-0680-0522
Armaan GurayaMidwestern University Chicago College of Osteopathic Medicine, Chicago, IL, 60515, USA.ORCID https://orcid.org/0000-0003-1876-3586
Kamaria NelsonDepartment of Dermatology, George Washington School of Medicine, Washington, DC, 20052, USA.
Brittany ManerRoss University School of Medicine, St. Michael, Barbados, BB, 11093, USA.
Jaya ManjunathDepartment of Dermatology, George Washington School of Medicine, Washington, DC, 20052, USA.
Gabrielle SchwartzmanDepartment of Dermatology, George Washington School of Medicine, Washington, DC, 20052, USA.
Brittany LaneMichigan State University College of Human Medicine, East Lansing, MI, 48824, USA.
Jonathan I SilverbergDepartment of Dermatology, George Washington School of Medicine, Washington, DC, 20052, USA. Jonathanisilverberg@gmail.com.ORCID https://orcid.org/0000-0003-3686-7805
George Washington University · USMichigan State University · USMidwestern University · USNorthwestern University · USRosalind Franklin University of Medicine and Science · USRoss University School of Medicine · BB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atopic dermatitis is characterized by immune dysregulation, which may predispose toward worse COVID-19 outcomes. We conducted a retrospective cohort study to investigate the relationship of atopic dermatitis with COVID-19 symptom severity, hospitalization, length of hospital stay, requirement for oxygen therapy, long-term morbidity and mortality. Multivariable logistic regression models were constructed to examine the impact of atopic dermatitis (independent variable) on COVID-19 symptom severity, hospitalization, length of hospital stay, requirement for oxygen therapy, long-term morbidity and mortality (dependent variables). SARS-CoV-2 positive adult patients with diagnosed AD had similar odds of hospitalization (adjusted odds ratio [95% confidence interval]: 0.51 [0.20-1.35]), acute level of care at initial medical care (0.67 [0.35-1.30]), severe-critical SARS-CoV-2 (0.82 [0.29-2.30]), requirement of supplemental non-mechanical oxygen therapy (1.33 [0.50-3.58]), extended hospital stay (2.24 [0.36-13.85]), lingering COVID-19 symptoms (0.58 [0.06-5.31]) and COVID-19 death (0.002 [< 0.001- > 999]) compared to patients without AD. Our findings suggest AD is not an independent risk factor for COVID-19 severity or complications.

Indexed as

COVID-19Dermatitis, AtopicAdultHumansOxygenRetrospective StudiesSARS-CoV-2OxygenAtopic dermatitisCOVID-19EpidemiologySARS-CoV-2

Identifiers

PMID34533589
PMCPMC8447890
OpenAlexW3199198322

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.