Evidence map›Paper›PMID 34533572›Full record

ArticleJAMA network open2021

Changes in Emergency Department Encounters for Vomiting After Cannabis Legalization in Colorado.

George Sam Wang, Christine Buttorff, Asa Wilks, Daniel Schwam, Gregory Tung, Rosalie Liccardo Pacula

Abstract read
In one paragraph

Article in JAMA network open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

George Sam WangDepartment of Pediatrics, University of Colorado Anschutz Medical Campus, Children's Hospital Colorado, Aurora.
Christine ButtorffRAND Corporation, Arlington, Virginia.
Asa WilksRAND Corporation, Santa Monica, California.
Daniel SchwamRAND Corporation, Arlington, Virginia.
Gregory TungDepartment of Health Systems, Management & Policy, Colorado School of Public Health, University of Colorado Anschutz Medical Campus.
Rosalie Liccardo PaculaSol Price School of Public Policy, Schaeffer Center for Health Policy & Economics, University of Southern California, Los Angeles.

Funding

Impact of Marijuana Legalization on Opioid Prescribing and Poisonings in ColoradoR01DA045051 · NIDA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI PACULA, ROSALIE LICCARDO · 2018 to 2020
$1.7M
NIDA NIH HHS R01 DA045051
6 · The paper itself

Abstract

Importance: Cannabis hyperemesis syndrome is an emerging clinical issue associated with cannabis use. Legalization of cannabis has led to an increase in vomiting-related illnesses in health care settings. Objective: To examine whether legalization of cannabis in Colorado has been associated with increases in vomiting-related emergency department (ED) visits. Design, Setting, and Participants: A cross-sectional design was used to assess the increase in ED claims for vomiting reported to the Colorado Hospital Association between January 1, 2013, and December 31, 2018, in counties that had no prior cannabis dispensaries before legalization compared with those that did. A total of 820 778 patients seeking care through Colorado EDs were included in the analysis. Exposures: The number of medical and recreational cannabis dispensaries per county per quarter. Main Outcomes and Measures: County per capita rate of vomiting-related ED claims per quarter. Results: Vomiting-related ED health care encounters increased from 119 312 in 2013 to 153 699 in 2018 (29% increase). Over this period, 203 861 patients (25%) were aged 0 to 18 years; 114 201 (14%) were aged 19 to 25 years, and 502 771 (61%) were aged 26 years or older; 510 584 patients (62%) were female. Additional recreational dispensaries were associated with increased vomiting-related ED visits (incidence rate ratio, 1.03; 95% CI, 1.01-1.05), but counties with high baseline medical dispensary exposure experienced smaller increases in vomiting-related ED visits than counties with no baseline medical dispensary exposure (incidence rate ratio, 0.97; 95% CI, 0.95-0.99). Counties with a high number of medical marijuana dispensaries had increases at a 5.8% slower rate than counties with none. Conclusions and Relevance: The findings of this study suggest that cannabis legalization in Colorado is associated with an increase in annual vomiting-related health care encounters with regard to exposure to these markets. It may be useful for health care clinicians to be aware of cannabis hyperemesis syndrome and inquire about cannabis use when appropriate.

Indexed as

Legislation, DrugAdolescentAdultChildChild, PreschoolColoradoCross-Sectional StudiesEmergency Service, HospitalFemaleHumansIncidenceInfantInfant, NewbornMaleMedical MarijuanaSyndromeMedical Marijuana

Identifiers

PMID34533572
PMCPMC8449280

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.