Evidence map›Paper›PMID 34533104›Full record

ArticleActa orthopaedica2022

Similar periprosthetic joint infection rates after and before a national infection control program: a study of 45,438 primary total knee arthroplasties.

Olof Thompson, Annette W-Dahl, Viktor Lindgren, Max Gordon, Otto Robertsson, Anna Stefánsdóttir

Open access · goldAbstract read
In one paragraph

Article in Acta orthopaedica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Staphylococcus aureus From Prosthetic Joint Infections and Blood Cultures Display the Same Genetic Background.APMIS : acta pathologica, microbiologica, et immunologica Scandinavica · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Observational
  11. Article
  12. Article
  13. No component loosening of a cementless deep dish rotating platform knee at a 5-year follow-up.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2023
    Observational
  14. Microorganisms · 2023
    Article
  15. Article
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Olof Thompson. olof.thompson@med.lu.se.
Annette W-DahlSwedish Knee Arthroplasty Register, Lund, Sweden; Department of Clinical Sciences Lund, Lund University, Division of Orthopedics. annette.w-dahl@med.lu.se.
Viktor LindgrenDepartment of Molecular Medicine and Surgery, Section of Orthopedics, Karolinska Institute, Stockholm, Sweden. viktor.lindgren@sll.se.
Max GordonDepartment of Clinical Sciences at Danderyd Hospital, Division of Orthopedics, Karolinska Institutet, Stockholm, Sweden. max@gforge.se.
Otto RobertssonSwedish Knee Arthroplasty Register, Lund, Sweden; Department of Clinical Sciences Lund, Lund University, Division of Orthopedics. otto.robertsson@med.lu.se.
Anna StefánsdóttirDepartment of Clinical Sciences Lund, Lund University, Division of Orthopedics; Department of Orthopedics, Skåne University Hospital, Lund, Sweden. anna.stefansdottir@med.lu.se.
Karolinska Institutet · SELund University · SESkåne University Hospital · SEThe Swedish Hip Arthroplasty Register · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and purpose - Strenuous efforts to minimize postoperative infection rates have been made, including the Swedish nationwide initiative Prosthesis Related Infections Shall be Stopped (PRISS). This study calculated the incidence rate of periprosthetic joint infection (PJI) following primary total knee arthroplasty (TKA) before and after PRISS. Patients and methods - All 45,438 primary TKAs registered in the Swedish Knee Arthroplasty Register (SKAR) during 2007-2008 and 2012-2013 were included. Matched data on antibiotic prescriptions were obtained from the Swedish Prescribed Drug Register (SPDR). All patients with ≥ 28 days of continuous antibiotic treatment within 2 years of primary surgery had their medical charts reviewed to identify cases of PJI. The incidence rate was calculated by dividing the number of PJIs by the total time at risk during each time period and presented as percentages with 95% confidence interval (CI). Results - 644 PJIs were identified, equaling a 2-year incidence rate of 1.45% (CI 1.34-1.57). The incidence rate was 1.44% (CI 1.27-1.61) before PRISS and 1.46% (CI 1.31-1.61) after. Diagnosis was made within 30 days of primary TKA in 52%, and within 90 days in 73% of cases. 603 cases were reoperated on or revised. Median time from operation to diagnosis was 29 days (1-716), for both time periods. Debridement with exchange of the insert was performed in 32% and 63% of cases before and after PRISS, respectively. Interpretation - We found similar incidence rates before and after the PRISS initiative without any statistically significant difference. Time to diagnosis was similar during both time periods. The project may have contributed to increased compliance with treatment protocols.

Indexed as

AgedAnti-Bacterial AgentsArthroplasty, Replacement, KneeFemaleHumansIncidenceInfection ControlMaleMiddle AgedProsthesis-Related InfectionsSwedenAnti-Bacterial Agents

Identifiers

PMID34533104
PMCPMC8815852
OpenAlexW3201517168

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.