Evidence map›Paper›PMID 34533073›Full record

ArticleScience progress

Neonatal exposure to sevoflurane caused learning and memory impairment via dysregulating SK2 channel endocytosis.

Wentao Ke, Xiangdi Yu, Yutong Gao

Open access · diamondAbstract read
In one paragraph

Article in Science progress. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Wentao KeXiangya School of Medicine, 47904Central South University, China.
Xiangdi YuDepartment of Anesthesiology, 56663Guizhou Provincial People's Hospital, The Affiliated Hospital of Guizhou University, China.ORCID 0000-0001-5010-3145
Yutong GaoDepartment of Anesthesiology, 56663Guizhou Provincial People's Hospital, The Affiliated Hospital of Guizhou University, China.
Guizhou University · CNCentral South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Numerous studies have demonstrated that anesthetics' exposure to neonates imposes toxicity on the developing brain but the underlying mechanisms need to be further elucidated. Our present study aimed to explore the role of small conductance Ca

Indexed as

HemagglutininsMemory DisordersAnimalsEndocytosisPotassium ChannelsRatsRats, Sprague-DawleySevofluraneHemagglutininsPotassium ChannelsSevofluraneNeonatal ratsevofluraneSK2 channel

Identifiers

PMID34533073
PMCPMC10461796
OpenAlexW3201230624

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.