Evidence map›Paper›PMID 34533043›Full record

ArticleJournal of the American Heart Association2021

Treatment Effect of Percutaneous Coronary Intervention in Men Versus Women With ST-Segment-Elevation Myocardial Infarction.

Samian Sulaiman, Akram Kawsara, Mohamed O Mohamed, Harriette G C Van Spall, Nadia Sutton, David R Holmes, Mamas A Mamas, Mohamad Alkhouli

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

  1. Gender-based differences among ST-elevation myocardial infarction patients in Egypt: secondary analysis from the ACCA-EAPCI ESC-STEMI registry.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2025
    Article
  2. Review
  3. Acute Coronary Syndrome in Women: An Update.Current cardiology reports · 2024
    Review
  4. Article
  5. Sex Differences in Acute Coronary Syndromes: A Global Perspective.Journal of cardiovascular development and disease · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

Samian SulaimanDivision of Cardiology West Virginia University Morgantown WV.
Akram KawsaraDivision of Cardiology West Virginia University Morgantown WV.
Mohamed O MohamedKeele Cardiovascular Research Group Centre for Prognosis Research Keele University Stoke-on-Trent United Kingdom.ORCID 0000-0002-9678-5222
Harriette G C Van SpallDepartment of Medicine Division of Cardiology McMaster University Hamilton Ontario Canada.ORCID 0000-0002-8370-4569
Nadia SuttonDivision of Cardiovascular Medicine Department of Internal Medicine University of Michigan Ann Arbor MI.ORCID 0000-0002-0968-3085
David R HolmesDepartment of Cardiovascular Disease Mayo Clinic Rochester MN.ORCID 0000-0002-0037-0373
Mamas A MamasKeele Cardiovascular Research Group Centre for Prognosis Research Keele University Stoke-on-Trent United Kingdom.ORCID 0000-0001-9241-8890
Mohamad AlkhouliDepartment of Cardiovascular Disease Mayo Clinic Rochester MN.ORCID 0000-0003-3847-0959
Keele University · GBMayo Clinic in Arizona · USWest Virginia University · USPopulation Health Research Institute · CAUniversity of Michigan · US

Funding

Ectonucleotidase modulation of age-dependent vascular calcification and stiffnessK76AG064426 · NIA · VANDERBILT UNIVERSITY MEDICAL CENTER · PI SUTTON, NADIA RAZAQ · 2020 to 2024
$1.2M
6 · The paper itself

Abstract

Background Women are less likely to receive primary percutaneous coronary intervention (pPCI) than men. A potential reason is risk aversion because of the worse outcomes with pPCI among women. However, whether pPCI is associated with a comparable mortality benefit in men and women remains unknown. Methods and Results We selected patients admitted with a principal diagnosis of ST-segment-elevation myocardial infarction in the National Inpatient Sample (2016-2018). We used propensity-score matching to calculate average treatment effects of pPCI for in-hospital mortality, major complications, length of stay, and cost. As a sensitivity analysis, we used logit models followed by a marginal command to calculate the average marginal effect. We included 413 500 weighted hospitalizations (30.7% women, 69.3% men). Women had more comorbidities except smoking and prior sternotomy. Compared with men, women were less likely to undergo angiography (81.0% versus 87.0%; adjusted odds ratio [OR], 0.77; 95% CI, 0.74-0.81;

Indexed as

Percutaneous Coronary InterventionST Elevation Myocardial InfarctionFemaleHumansMaleMiddle AgedSex FactorsTreatment Outcomemyocardial infarctionpercutaneous coronary interventionsex differencestreatment effect

Identifiers

PMID34533043
PMCPMC8649522
OpenAlexW3199632291

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.