Evidence map›Paper›PMID 34532716›Full record

ArticleCell reports methods2021

Uncovering biomarkers during therapeutic neuromodulation with PARRM: Period-based Artifact Reconstruction and Removal Method.

Evan M Dastin-van Rijn, Nicole R Provenza, Jonathan S Calvert, Ro'ee Gilron, Anusha B Allawala, Radu Darie, Sohail Syed, Evan Matteson, Gregory S Vogt, Michelle Avendano-Ortega and 10 more

Abstract read
In one paragraph

Article in Cell reports methods, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Effect of frequency on dual target deep brain stimulation.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Periodic Artifact Removal With Applications to Deep Brain Stimulation.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2022
    Article
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Evan M Dastin-van RijnBrown University School of Engineering, Providence, RI, USA.
Nicole R ProvenzaBrown University School of Engineering, Providence, RI, USA.
Jonathan S CalvertBrown University School of Engineering, Providence, RI, USA.
Ro'ee GilronDeparment of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA.
Anusha B AllawalaBrown University School of Engineering, Providence, RI, USA.
Radu DarieBrown University School of Engineering, Providence, RI, USA.
Sohail SyedDepartment of Neurosurgery, Warren Alpert School of Medicine of Brown University, Providence, RI, USA.
Evan MattesonBrown University School of Engineering, Providence, RI, USA.
Gregory S VogtMenninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX 77030, USA.
Michelle Avendano-OrtegaMenninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX 77030, USA.
Ana C VasquezMenninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX 77030, USA.
Nithya RamakrishnanMenninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX 77030, USA.
Denise N OswaltDepartment of Neurosurgery, Perelman School of Medicine, Philadelphia, PA, USA.
Kelly R BijankiDepartment of Neurosurgery, Baylor College of Medicine, Houston, TX, USA.
Robert WiltDeparment of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA.
Philip A StarrDeparment of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA.
Sameer A ShethDepartment of Neurosurgery, Baylor College of Medicine, Houston, TX, USA.
Wayne K GoodmanMenninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX 77030, USA.
Matthew T HarrisonDivision of Applied Mathematics, Brown University, Providence, RI, USA.
David A BortonBrown University School of Engineering, Providence, RI, USA.

Funding

Deep brain stimulation for depression using directional current steering an individualized network targetingUH3NS103549 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GOODMAN, WAYNE K, POURATIAN, NADER · 2017 to 2025
$8.7M
Measuring Automated Behavioral Observations & Vocal Expressions (ABOVE) while Recording from the BrainUH3NS100549 · NINDS · BAYLOR COLLEGE OF MEDICINE · PI GOODMAN, WAYNE K · 2016 to 2022
$7.8M
Accelerating Dissemination of Implantable Neurotechnology for Clinical ResearchU24NS113637 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BORTON, DAVID ALLENSON, DENISON, TIMOTHY · 2020 to 2024
$4.4M
Closed Loop Deep Brain Stimulation for Parkinson's DiseaseUH3NS100544 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI STARR, PHILIP ANDREW · 2016 to 2022
$4.1M
Mapping and Modulating the Spatiotemporal dynamics of socio-affective processing.R01MH127006 · NIMH · BAYLOR COLLEGE OF MEDICINE · PI BIJANKI, KELLY ROWE · 2021 to 2025
$3.2M
Training Program in Recovery and Restoration of CNS health and functionT32NS100663 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI LEIGH R HOCHBERG, JONATHAN ROSAND · 2017 to 2026
$2.5M
Brain Science Compute ClusterS10OD025181 · OD · BROWN UNIVERSITY · PI SANES, JEROME N · 2019 to 2019
$600k
NIH HHS S10 OD025181NIMH NIH HHS R01 MH127006NINDS NIH HHS T32 NS100663NINDS NIH HHS U24 NS113637NINDS NIH HHS UH3 NS100544NINDS NIH HHS UH3 NS100549NINDS NIH HHS UH3 NS103549
6 · The paper itself

Abstract

Advances in therapeutic neuromodulation devices have enabled concurrent stimulation and electrophysiology in the central nervous system. However, stimulation artifacts often obscure the sensed underlying neural activity. Here, we develop a method, termed Period-based Artifact Reconstruction and Removal Method (PARRM), to remove stimulation artifacts from neural recordings by leveraging the exact period of stimulation to construct and subtract a high-fidelity template of the artifact. Benchtop saline experiments, computational simulations, five unique

Indexed as

ArtifactsSignal Processing, Computer-AssistedAnimalsBiomarkersBrainCentral Nervous SystemHumansBiomarkers

Identifiers

PMID34532716
PMCPMC8443190

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.