Evidence map›Paper›PMID 34532314›Full record

ArticleFrontiers in bioengineering and biotechnology2021

Subject-Specific Alignment and Mass Distribution in Musculoskeletal Models of the Lumbar Spine.

Marie-Rosa Fasser, Moritz Jokeit, Mirjam Kalthoff, David A Gomez Romero, Tudor Trache, Jess G Snedeker, Mazda Farshad, Jonas Widmer

Open access · goldAbstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Not just alignment: body shape influences adult spinal deformity biomechanics.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  3. Abdominal wall tension after spinal deformity correction compromises postoperative biomechanics and may contribute to proximal junctional kyphosis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  4. Article
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  6. Review
  7. The triadic relationship between spinal posture, loading, and degeneration.Frontiers in bioengineering and biotechnology · 2025
    Article
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  9. Article
  10. Review
  11. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Marie-Rosa FasserDepartment of Orthopaedics, Balgrist University Hospital, Zurich, Switzerland.
Moritz JokeitDepartment of Orthopaedics, Balgrist University Hospital, Zurich, Switzerland.
Mirjam KalthoffInstitute for Biomechanics, ETH Zurich, Zurich, Switzerland.
David A Gomez RomeroInstitute for Biomechanics, ETH Zurich, Zurich, Switzerland.
Tudor TracheDepartment of Orthopaedics, Balgrist University Hospital, Zurich, Switzerland.
Jess G SnedekerDepartment of Orthopaedics, Balgrist University Hospital, Zurich, Switzerland.
Mazda FarshadDepartment of Orthopaedics, Balgrist University Hospital, Zurich, Switzerland.
Jonas WidmerDepartment of Orthopaedics, Balgrist University Hospital, Zurich, Switzerland.
Universitätsklinik Balgrist · CHInstitute for Biomedical Engineering · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Musculoskeletal modeling is a well-established method in spine biomechanics and generally employed for investigations concerning both the healthy and the pathological spine. It commonly involves inverse kinematics and optimization of muscle activity and provides detailed insight into joint loading. The aim of the present work was to develop and validate a procedure for the automatized generation of semi-subject-specific multi-rigid body models with an articulated lumbar spine. Individualization of the models was achieved with a novel approach incorporating information from annotated EOS images. The size and alignment of bony structures, as well as specific body weight distribution along the spine segments, were accurately reproduced in the 3D models. To ensure the pipeline's robustness, models based on 145 EOS images of subjects with various weight distributions and spinopelvic parameters were generated. For validation, we performed kinematics-dependent and segment-dependent comparisons of the average joint loads obtained for our cohort with the outcome of various published

Indexed as

automatized model generationbi-planar radiographymusculoskeletal modellingspine biomechanicsspine loading predictionsubject-specificitythoracolumbar alignmentupper body mass distribution

Identifiers

PMID34532314
PMCPMC8438119
OpenAlexW3197626672

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.