Evidence map›Paper›PMID 34532270›Full record

ArticleTranslational andrology and urology2021

Female chronic posterior urethritis is underestimated in patients with lower urinary tract symptoms.

Juanjuan Xie, Xin Li, Yufang Lü, Caisheng Huang, Xinyang Long, Yong Liu, Huaxiang Lu, Jianhua Long, Bo Chen, Zhigang Luo and 1 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Translational andrology and urology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Juanjuan XieDepartment of Urology, The First Affiliated Hospital of Guangxi Medical University, Guangxi Medical University, Nanning, China.
Xin LiDepartment of Urology, The Second Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, China.
Yufang LüDepartment of Urology, The First Affiliated Hospital of Guangxi Medical University, Guangxi Medical University, Nanning, China.
Caisheng HuangDepartment of Urology, The First Affiliated Hospital of Guangxi Medical University, Guangxi Medical University, Nanning, China.
Xinyang LongInstitute of Urology and Nephrology, The First Affiliated Hospital of Guangxi Medical University, Guangxi Medical University, Nanning, China.
Yong LiuDepartment of Urology, The Second Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, China.
Huaxiang LuSchool of Public Health, Guangxi Medical University, Nanning, China.
Jianhua LongDepartment of Urology, The Second Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, China.
Bo ChenDepartment of Computer Center, The Second Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, China.
Zhigang LuoDepartment of Urology, The Second Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, China.
Zengnan MoDepartment of Urology, The First Affiliated Hospital of Guangxi Medical University, Guangxi Medical University, Nanning, China.
University of South China · CNFirst Affiliated Hospital of GuangXi Medical University · CNGuangxi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAs one of the causes of urethral symptoms, female chronic posterior urethritis is a common and distressing disease; however, it is often neglected and misdiagnosed as overactive bladder (OAB) or interstitial cystitis/bladder pain syndrome (IC/BPS). Currently, little is known about the urothelium and lamina propria of the bladder neck and proximal urethra. Thus, identifying urethral lesions is necessary for the diagnosis and treatment of female chronic posterior urethritis. Transurethral electroresection is an effective and safe approach for treating female chronic posterior urethritis. This study sought to determine if urethral lesions are necessary for the diagnosis and treatment of female chronic posterior urethritis, and evaluate the efficacy and safety of the transurethral electroresection of mucosa and submucosa in treating female chronic posterior urethritis.

methodsA single-center, retrospective, observational study was conducted at a teaching and referral hospital. A total of 147 female patients who had been diagnosed with chronic papillary urethritis underwent transurethral electroresection between 2015 and 2018. Each patient underwent a follow-up examination. A chart review was also performed.

resultsPatients had a mean age of 54 years (range, 23-82 years), and the average follow-up period was 54.8 months (range, 6-600 months). Urinary frequency and urgency (51.7%) were the most common clinical manifestations of chronic posterior urethritis. Forty-two-point two percent of patients had positive urine culture results, most commonly with Mycoplasma genitalium. The cystoscopic findings revealed that chronic posterior urethritis has tuft-like, pseudopodia-like, finger-like, and follicular-like polyps and villi, and a pebble-like appearance with mucosal hyperemia. The success rate of the transurethral electroresection was 88.6%, and patients showed no apparent or serious complications.

conclusionsThis study showed that female chronic posterior urethritis is a cause that contributes to LUT symptoms. Its characteristic cystoscopic appearance and biopsy play a vital role in its diagnosis. The transurethral electroresection of urethral lesions is simple, effective, and minimally invasive without any apparent complications.

Indexed as

Chronic polypoid urethritisfemale posterior urethritislower urinary tract symptoms (LUT symptoms)transurethral electroresectionurethral syndrome

Identifiers

PMID34532270
PMCPMC8421815
OpenAlexW3192402438

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.