ReviewEFORT open reviews2021
Giant cell tumour of bone around the knee: a systematic review of the functional and oncological outcomes.
Review in EFORT open reviews, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed.
- Optimal management of giant cell tumor in the tibial plateau: A case report on curettage and cement reinforcement.Radiology case reports · 2026Article
- Clinical and Radiological Concordance of Bone Tumours Using Histopathology as the Gold Standard: A Pilot Study.Cureus · 2026Article
- Revision total knee arthroplasty with long-stem prosthesis following primary knee replacement for giant cell tumor with fracture: a case report.Journal of surgical case reports · 2025Article
- Functional Outcomes of Surgical Treatment for Giant Cell Tumors around the Knee.Journal of orthopaedic case reports · 2025Article
- A New Relevant Integrated Radiologic and Surgical Classification Scheme for Giant Cell Tumors of Bones.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2025Article
- Article
- Primary malignant giant cell tumor (PMGCT): Diagnosis and management challenges in low resource settings.Narra J · 2025Article
- 30 YEARS OF BONE GIANT CELL TUMOR IN THE KNEE: A BRAZILIAN PERSPECTIVE.Acta ortopedica brasileira · 2025Article
- Article
- Review
- Malignant Transformation of Giant Cell Tumour of Bone: A Review of Literature and the Experience of a Referral Centre.International journal of molecular sciences · 2022Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Giant cell tumour of bone (GCT) is a relatively rare, locally aggressive benign neoplasm observed in the long bone epiphyseal-metaphyseal regions of young adults.The optimal treatment strategy for these tumours remains controversial, and a huge amount of contradictory data regarding the functional and oncological outcomes can be found. Therefore, we performed a systematic review intended to investigate the functional and oncological outcomes after surgical treatment of GCTs arising around the knee, namely in the distal femur and proximal tibia.A trend towards better oncological control was found using wide resections, nonetheless, curettage-based techniques achieve a highly acceptable recurrence rate with overall better knee function. A slight advantage favouring proximal tibia GCTs regarding the Musculoskeletal Tumor Society (MSTS) score was also observed.Prospective studies comparing groups of more homogeneous patients, tumours, and treatment options should be developed to obtain more conclusive and definitive results regarding the optimal strategy for treating GCTs. Cite this article:
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.